Klebsiella pneumoniae strain EuSCAPE_ES105

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES105 is a Gram-negative, rod-shaped bacterium exhibiting a range of pathogenic effects in humans and other hosts. It is a chemoheterotrophic organism that thrives as a facultative anaerobe, allowing it to adapt to varying oxygen levels. The strain is capable of mobility, equipped with flagella, and typically forms chains, pairs, or exists as single cells. EuSCAPE_ES105 has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, suggesting its adaptation to human hosts. This strain has a unique biotic relationship as it is classified as free-living, yet it is associated with numerous hosts, including Homo sapiens, various mammals, birds, and some plant species. The health impacts of Klebsiella pneumoniae strain EuSCAPE_ES105 are significant, contributing to a range of serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. The bacterium's ability to cause conditions like pyogenic liver abscesses and neonatal sepsis underlines its pathogenic potential. With its capability to inhabit diverse environments and infect various hosts, Klebsiella pneumoniae strain EuSCAPE_ES105 exemplifies the complex interactions between pathogenic bacteria and their hosts. Its environmental adaptability and pathogenicity highlight the importance of monitoring such strains in clinical and ecological settings, particularly in relation to their role in human health and disease transmission.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES105

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES105
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES105 genome assembly,

Gene Summary

Adenine Count

1243432 bp

Thymine Count

1245874 bp

Guanine Count

1634499 bp

Cytosine Count

1659591 bp

Genome Length

5783396 bp

Protein-coding Genes

5192 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
high-affinity branched-chain amino acid transporter permease livhSAMEA3538977_03082Not AvailableNegative3327395 - 332829432189.6
abc transport system periplasmic binding componentSAMEA3538977_03083Not AvailableNegative3328314 - 332945040105.8
ethanolamine ammonia-lyase light subunitSAMEA3538977_03084Not AvailableNegative3329997 - 333077328086.9
ethanolamine ammonia-lyase heavy subunitSAMEA3538977_03085Not AvailableNegative3330770 - 333215849940.2
ethanolamine permeaseSAMEA3538977_03086Not AvailableNegative3332168 - 333354749004.1
lysine-specific permeaseSAMEA3538977_03087Not AvailablePositive3333821 - 333523050785.0
homocysteine s-methyltransferaseSAMEA3538977_03088Not AvailablePositive3335217 - 333614933156.3
taurine-binding periplasmic protein tauaSAMEA3538977_03089Not AvailablePositive3336389 - 333735134198.8
taurine transport atp-binding protein taubSAMEA3538977_03090Not AvailablePositive3337363 - 333813028157.2
taurine transport system permease taucSAMEA3538977_03091Not AvailablePositive3338127 - 333895429426.3

Displaying genes 3251 – 3260 of 5498 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total