Klebsiella pneumoniae strain EuSCAPE_ES083

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES083 is a Gram-negative, rod-shaped bacterium that exhibits a versatile lifestyle as a chemoheterotroph and facultative anaerobe. This strain is capable of existing in various forms, including chains, pairs, and singles, and possesses flagella, allowing for mobility. The optimal growth temperature for this strain is 37°C, indicating its mesophilic nature. This bacterium is primarily found in host-associated environments and has a wide range of hosts, including Homo sapiens, Gallus gallus, and several other species across Metazoa, Viridiplantae, and Aves. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_ES083 is significant, as it is linked to numerous health issues such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its ability to cause severe conditions like sepsis and meningitis highlights its clinical importance. Additionally, the strain's biotic relationships are characterized as free-living, despite its pathogenic potential in humans and animals. The presence of a single replicon and two membranes is indicative of its structural complexity and adaptability. The ecological insight provided by this bacterium's broad host range and pathogenic capabilities suggests its potential role in both environmental reservoirs and as a significant public health threat. The diverse diseases it can cause emphasize the need for ongoing surveillance and research to understand its behavior and to develop effective treatment strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES083

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES083
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES083 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

5157 genes

Non-Coding Genes

183 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribonuclease iSAMEA3538955_01174Not AvailablePositive1307744 - 130854129125.7
regulator of nucleoside diphosphate kinaseSAMEA3538955_01175Not AvailablePositive1308720 - 130913014868.8
universal stress protein gSAMEA3538955_01176Not AvailablePositive1309317 - 130974515953.4
alkyl hydroperoxide reductase protein fSAMEA3538955_01177Not AvailableNegative1309822 - 131138756036.0
alkyl hydroperoxide reductase protein cSAMEA3538955_01178Not AvailableNegative1311575 - 131213820764.5
thiol:disulfide interchange protein dsbgSAMEA3538955_01179Not AvailablePositive1312550 - 131329927923.2
lysr-family transcriptional regulator ybdoSAMEA3538955_01180Not AvailablePositive1313480 - 131441235750.1
co-activator of prophage gene expression ibraSAMEA3538955_01181Not AvailablePositive1314523 - 131574647902.0
co-activator of prophage gene expression ibrbSAMEA3538955_01182Not AvailablePositive1315731 - 131635723573.4
methionine aminotransferaseSAMEA3538955_01183Not AvailableNegative1316358 - 131751842790.2

Displaying genes 1281 – 1290 of 5340 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total