Klebsiella pneumoniae strain EuSCAPE_HU006

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU006 is a gram-negative, rod-shaped bacterium characterized by its ability to thrive in host-associated habitats. As a chemoheterotroph, it utilizes organic compounds for energy and exhibits facultative anaerobic respiration, allowing flexibility in oxygen availability. This strain typically forms chains, pairs, or singles and possesses flagella, which contribute to its mobility. Its optimal growth temperature is 37°C, indicative of its mesophilic nature. Klebsiella pneumoniae strain EuSCAPE_HU006 is known for its pathogenicity in humans, causing a range of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. It can infect various hosts, including Homo sapiens, Gallus gallus, and several other metazoans, highlighting its ecological versatility and ability to adapt to different biological environments. In terms of structural biology, this strain contains one replicon and is surrounded by two membranes, characteristic of gram-negative bacteria. Notably, it does not form spores, which is a common trait among many pathogenic bacteria. The versatility of Klebsiella pneumoniae strain EuSCAPE_HU006 in infecting multiple hosts suggests its ecological role as a significant pathogen, capable of causing severe infections in both human and animal populations. This capacity underscores the importance of monitoring its spread and understanding its mechanisms of pathogenicity to address public health concerns effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU006 genome assembly,

Gene Summary

Adenine Count

1190444 bp

Thymine Count

1194759 bp

Guanine Count

1598578 bp

Cytosine Count

1590446 bp

Genome Length

5574227 bp

Protein-coding Genes

5071 genes

Non-Coding Genes

181 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glycine cleavage system transcriptional activatorSAMEA3538755_00987Not AvailableNegative1073582 - 107447532761.7
glutathione s-transferase, unnamed subgroup 2SAMEA3538755_00988Not AvailablePositive1074729 - 107533422282.1
short chain dehydrogenaseSAMEA3538755_00989Not AvailableNegative1075387 - 107617227689.1
3-oxoacyl-acp reductaseSAMEA3538755_00990Not AvailableNegative1076373 - 107717029253.8
ribose abc transporter permease rbscSAMEA3538755_00991Not AvailableNegative1077231 - 107829837441.3
sugar abc transporter atp-binding proteinSAMEA3538755_00992Not AvailableNegative1078316 - 107986056784.1
lipoproteinSAMEA3538755_00993Not AvailableNegative1079862 - 108015510437.3
pts system proteinSAMEA3538755_00994Not AvailableNegative1080695 - 108099711331.6
pts system proteinSAMEA3538755_00995Not AvailableNegative1081095 - 108241748198.3
pts system cellobiose-specific transporter subunit iibSAMEA3538755_00996Not AvailableNegative1082429 - 108274311577.2

Displaying genes 1101 – 1110 of 5252 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total