Klebsiella pneumoniae strain EuSCAPE_ES063

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES063 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain typically exhibits a variety of cell arrangements, including chains, pairs, and singles. It possesses flagella, which contributes to its mobility. The optimal growth temperature for EuSCAPE_ES063 is 37°C, categorizing it as mesophilic. This strain is host-associated, with a diverse range of hosts including Homo sapiens, various birds (Gallus gallus, Phasianidae, Aves), mammals (Canis lupus familiaris, Sus scrofa, Equidae), amphibians, and several plant species (Viridiplantae). Its ability to thrive in various environments highlights its ecological versatility, allowing it to inhabit multiple biological niches. EuSCAPE_ES063 is notable for its pathogenicity in humans, being associated with a wide array of health effects. It can cause serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis, along with other conditions like liver abscesses and meningitis. These health implications underscore the bacterium's clinical significance and its role in healthcare-associated infections. Given its pathogenic potential and broad host range, Klebsiella pneumoniae strain EuSCAPE_ES063 exemplifies the complexities of microbial interactions within host organisms and the necessity for ongoing surveillance and research. Understanding its behavior and impact on both human health and animal populations is crucial for effective management and treatment strategies in microbiology and healthcare.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES063

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES063
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES063 genome assembly,

Gene Summary

Adenine Count

1249771 bp

Thymine Count

1240474 bp

Guanine Count

1613940 bp

Cytosine Count

1636535 bp

Genome Length

5740720 bp

Protein-coding Genes

5356 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphatase yidaSAMEA3538935_04056Not AvailablePositive4312715 - 431352729491.6
lipoproteinSAMEA3538935_04057Not AvailablePositive4313698 - 431475938521.8
outer membrane protein/protective antigen oma87SAMEA3538935_04058Not AvailablePositive4314756 - 431588942226.4
d-galactonate repressor dgorSAMEA3538935_04059Not AvailablePositive4316119 - 431680826053.0
2-dehydro-3-deoxygalactonokinaseSAMEA3538935_04060Not AvailablePositive4316805 - 431768331165.2
2-dehydro-3-deoxyphosphogluconate aldolaseSAMEA3538935_04061Not AvailablePositive4317667 - 431828421471.9
galactonate dehydrataseSAMEA3538935_04062Not AvailablePositive4318281 - 431942942547.3
d-galactonate transporterSAMEA3538935_04063Not AvailablePositive4319652 - 432094447191.4
protein of uncharacterised function (duf3748)SAMEA3538935_04064Not AvailablePositive4320996 - 432222244959.5
outer membrane lipoprotein yidqSAMEA3538935_04065Not AvailableNegative4322224 - 432255611806.3

Displaying genes 4061 – 4070 of 5438 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total