Klebsiella pneumoniae strain EuSCAPE_ES050

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES050 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically forms chains, pairs, or singles in its cellular arrangement. It thrives optimally at 37°C and falls within the mesophilic temperature range. Ecologically, EuSCAPE_ES050 is host-associated, suggesting a relationship with various organisms, including Homo sapiens, Gallus gallus, and other metazoans. Its free-living nature indicates it can exist independently in specific environments while maintaining associations with these hosts. The strain has been implicated in numerous health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. These infections can have significant health implications, particularly in vulnerable populations. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_ES050 primarily affects humans but extends to a range of other hosts, highlighting its versatility and potential for cross-species transmission. This strain's ability to cause a wide array of infections demonstrates its adaptability and resilience in various biological contexts. Such traits underscore the importance of understanding Klebsiella pneumoniae in both clinical and environmental microbiology, as it plays a critical role in human health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES050

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES050
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES050 genome assembly,

Gene Summary

Adenine Count

1240727 bp

Thymine Count

1237454 bp

Guanine Count

1627627 bp

Cytosine Count

1639550 bp

Genome Length

5745358 bp

Protein-coding Genes

5143 genes

Non-Coding Genes

275 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
puta and putp / proline dehydrogenase transcriptional repressorSAMEA3538922_03761Not AvailablePositive3975163 - 3979125144507.0
secreted proteinSAMEA3538922_03762Not AvailablePositive3979311 - 397970614047.7
transcriptional regulator rutrSAMEA3538922_03763Not AvailableNegative3979703 - 398034123471.6
monooxygenase ruta in pyrimidine catabolism pathwaySAMEA3538922_03764Not AvailablePositive3980626 - 398171739933.4
amidohydrolase rutb in pyrimidine catabolism pathwaySAMEA3538922_03765Not AvailablePositive3981717 - 398242725832.7
ring-opening amidohydrolase rutc in pyrimidine catabolism pathwaySAMEA3538922_03766Not AvailablePositive3982420 - 398281213868.7
hydrolase or acyltransferase rutdSAMEA3538922_03767Not AvailablePositive3982809 - 398361228413.3
reductase ruteSAMEA3538922_03768Not AvailablePositive3983609 - 398419921597.6
putative flavin:nadh reductaseSAMEA3538922_03769Not AvailablePositive3984210 - 398470417635.1
uracil permeaseSAMEA3538922_03770Not AvailablePositive3984726 - 398604845269.9

Displaying genes 3781 – 3790 of 5418 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total