Klebsiella pneumoniae strain EuSCAPE_IT365

Klebsiella pneumoniae strain EuSCAPE_IT365 is a Gram-negative, rod-shaped bacterium that exhibits a range of pathogenic characteristics, making it a significant concern in clinical settings. This strain is a facultative anaerobe and utilizes a chemoheterotrophic metabolism, allowing it to thrive in various environments, particularly those associated with human hosts. It is capable of forming chains, pairs, or existing as single cells, and displays mobility due to the presence of flagella. Optimal growth occurs at 37°C, aligning with the typical human body temperature, and it falls within the mesophilic temperature range. EuSCAPE_IT365 has a biotic relationship characterized as free-living, yet it is associated with numerous hosts, including Homo sapiens and various animal species such as Gallus gallus and Sus scrofa. The health implications of this strain are extensive, as it is linked to a wide array of infections including bacteremia, pneumonia, urinary tract infections, and more severe conditions such as sepsis and meningitis. The strain's ability to cause infections across different systems underscores its pathogenicity in humans, particularly in vulnerable populations. The presence of a single replicon and a double membrane structure is typical for this genus, which is known for its resilience and adaptability. The ecological insight from K. pneumoniae strain EuSCAPE_IT365 is its role in both commensal and pathogenic contexts within diverse host organisms, indicating its potential for transmission across species and its impact on public health.