Klebsiella pneumoniae strain EuSCAPE_IT337

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT337 is a Gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic effects in humans and other hosts. This organism is a facultative anaerobe, thriving optimally at 37°C, which categorizes it as mesophilic. It possesses flagella, indicating mobility, and is capable of existing in various arrangements including chains, pairs, and singles. As a chemoheterotroph, EuSCAPE_IT337 derives its energy from organic compounds, associating closely with a range of hosts, including Homo sapiens, Gallus gallus, and several other vertebrates and invertebrates. Its biotic relationships are free-living, allowing it to interact with different ecosystems. The strain is noted for its pathogenic potential, causing a wide array of health issues such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. This broad spectrum of pathogenic effects highlights its role as a significant opportunistic pathogen in clinical settings, particularly in immunocompromised individuals. The presence of multiple hosts indicates the ecological versatility of Klebsiella pneumoniae strain EuSCAPE_IT337, underscoring its potential to adapt to different environments and organisms. Understanding its biology and pathogenic mechanisms is crucial for developing effective treatment and prevention strategies against the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT337

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT337
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT337 genome assembly,

Gene Summary

Adenine Count

1221924 bp

Thymine Count

1214200 bp

Guanine Count

1628683 bp

Cytosine Count

1621668 bp

Genome Length

5686475 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l22SAMEA3538705_05058Not AvailablePositive5265109 - 526544112196.9
30s ribosomal protein s3SAMEA3538705_05059Not AvailablePositive5265459 - 526615725840.6
50s ribosomal protein l16SAMEA3538705_05060Not AvailablePositive5266170 - 526658015251.0
50s ribosomal protein l29SAMEA3538705_05061Not AvailablePositive5266580 - 52667717243.93
30s ribosomal protein s17SAMEA3538705_05062Not AvailablePositive5266771 - 52670259704.05
50s ribosomal protein l14SAMEA3538705_05063Not AvailablePositive5267191 - 526756213555.9
50s ribosomal protein l24SAMEA3538705_05064Not AvailablePositive5267573 - 526788711316.9
50s ribosomal protein l5SAMEA3538705_05065Not AvailablePositive5267902 - 526844120302.7
30s ribosomal protein s14SAMEA3538705_05066Not AvailablePositive5268456 - 526876111579.2
30s ribosomal protein s8SAMEA3538705_05067Not AvailablePositive5268795 - 526918714099.4

Displaying genes 5131 – 5140 of 5507 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total