Klebsiella pneumoniae strain EuSCAPE_IT322

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT322 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism and relies on chemoheterotrophic energy sources. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles, and it possesses flagella that confer mobility. The optimal growth temperature for EuSCAPE_IT322 is 37°C, placing it within the mesophilic temperature range. As a host-associated organism, Klebsiella pneumoniae strain EuSCAPE_IT322 has a diverse array of potential hosts, including Homo sapiens, various species of birds (Phasianidae, Aves), mammals (such as Sus scrofa and Canis lupus familiaris), amphibians, and even some plant species (Viridiplantae). This broad range of hosts highlights its ecological versatility and potential for interaction with different biological systems. Clinically, this strain is associated with significant health concerns, including bacteremia, urinary tract infections, pneumonia, and a variety of other severe conditions such as sepsis and meningitis. Its pathogenicity in humans underscores its importance in clinical microbiology, particularly in relation to hospital-acquired infections. The biological implications of Klebsiella pneumoniae strain EuSCAPE_IT322's ability to infect multiple hosts and cause a wide range of diseases suggest a complex ecological role within both human and non-human environments. This strain exemplifies the challenges of managing infections in healthcare settings, particularly due to its virulence and adaptability to various ecological niches.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT322

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT322
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT322 genome assembly,

Gene Summary

Adenine Count

1227960 bp

Thymine Count

1224411 bp

Guanine Count

1619203 bp

Cytosine Count

1644467 bp

Genome Length

5716041 bp

Protein-coding Genes

5141 genes

Non-Coding Genes

411 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phenylacetate-coa oxygenaseSAMEA3538690_02894Not AvailableNegative3003205 - 300349210934.8
phenylacetate-coa oxygenaseSAMEA3538690_02895Not AvailableNegative3003504 - 300443335265.8
bifunctional aldehyde dehydrogenase/enoyl-coa hydrataseSAMEA3538690_02896Not AvailablePositive3004720 - 300676572959.6
monoamine oxidaseSAMEA3538690_02897Not AvailablePositive3007242 - 300950983621.9
oxidoreductaseSAMEA3538690_02898Not AvailableNegative3009512 - 301046233977.4
2-dehydropantoate 2-reductaseSAMEA3538690_02899Not AvailableNegative3010539 - 301142931331.0
phenylacetaldehyde dehydrogenaseSAMEA3538690_02900Not AvailableNegative3011553 - 301305253582.0
dna-binding transcriptional activator fearSAMEA3538690_02901Not AvailablePositive3013288 - 301419033599.1
uncharacterized protein conserved in bacteriaSAMEA3538690_02902Not AvailableNegative3014191 - 301451411699.2
lipoproteinSAMEA3538690_02903Not AvailableNegative3014522 - 30147076833.62

Displaying genes 3081 – 3090 of 5552 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total