Klebsiella pneumoniae strain EuSCAPE_IT264

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT264 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is characterized by its mobility, facilitated by the presence of flagella, and it typically forms chains, pairs, or single cells. The optimal growth temperature for EuSCAPE_IT264 is 37°C, placing it within the mesophilic temperature range. EuSCAPE_IT264 is primarily host-associated, showing a wide spectrum of potential hosts, including Homo sapiens and various animal species such as Gallus gallus (chickens), Canis lupus familiaris (dogs), and Sus scrofa (pigs). This bacterium is known for its pathogenicity in humans, causing a variety of severe health conditions. Reported infections include bacteremia, urinary tract infections, pneumonia, and more complex conditions like pyogenic liver abscesses and neonatal sepsis. Klebsiella pneumoniae is significant not only due to its pathogenic effects but also because of its ecological role as a free-living organism. Its ability to thrive in diverse environments, coupled with its pathogenic potential, underlines the importance of monitoring its presence in both clinical and environmental settings. This duality emphasizes the need for ongoing research into its transmission dynamics and resistance mechanisms, particularly given its association with serious infections in a range of hosts. Understanding the ecological interactions of EuSCAPE_IT264 could provide insights into its adaptability and the challenges it presents in healthcare settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT264

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT264
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT264 genome assembly,

Gene Summary

Adenine Count

1187747 bp

Thymine Count

1185718 bp

Guanine Count

1584017 bp

Cytosine Count

1580501 bp

Genome Length

5537983 bp

Protein-coding Genes

4975 genes

Non-Coding Genes

388 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transport proteinSAMEA3538631_00478Not AvailablePositive476175 - 47745846396.4
putative enzymeSAMEA3538631_00479Not AvailableNegative477510 - 47844234516.6
glutamate synthase subunit alphaSAMEA3538631_00480Not AvailablePositive479116 - 483576163355.0
glutamate synthase small subunitSAMEA3538631_00481Not AvailablePositive483586 - 48500451913.1
n-acetylmannosamine-6-phosphate 2-epimeraseSAMEA3538631_00482Not AvailableNegative485059 - 48576324488.5
clpxp protease specificity-enhancing factor / stringent starvation protein bSAMEA3538631_00483Not AvailableNegative485888 - 48638217982.1
stringent starvation protein aSAMEA3538631_00484Not AvailableNegative486386 - 48702424191.2
30s ribosomal protein s9SAMEA3538631_00485Not AvailableNegative487336 - 48772814857.1
50s ribosomal protein l13SAMEA3538631_00486Not AvailableNegative487744 - 48817216110.6
atpaseSAMEA3538631_00487Not AvailableNegative488438 - 48956542498.3

Displaying genes 831 – 840 of 5363 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total