Klebsiella pneumoniae strain EuSCAPE_IT264

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT264 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is characterized by its mobility, facilitated by the presence of flagella, and it typically forms chains, pairs, or single cells. The optimal growth temperature for EuSCAPE_IT264 is 37°C, placing it within the mesophilic temperature range. EuSCAPE_IT264 is primarily host-associated, showing a wide spectrum of potential hosts, including Homo sapiens and various animal species such as Gallus gallus (chickens), Canis lupus familiaris (dogs), and Sus scrofa (pigs). This bacterium is known for its pathogenicity in humans, causing a variety of severe health conditions. Reported infections include bacteremia, urinary tract infections, pneumonia, and more complex conditions like pyogenic liver abscesses and neonatal sepsis. Klebsiella pneumoniae is significant not only due to its pathogenic effects but also because of its ecological role as a free-living organism. Its ability to thrive in diverse environments, coupled with its pathogenic potential, underlines the importance of monitoring its presence in both clinical and environmental settings. This duality emphasizes the need for ongoing research into its transmission dynamics and resistance mechanisms, particularly given its association with serious infections in a range of hosts. Understanding the ecological interactions of EuSCAPE_IT264 could provide insights into its adaptability and the challenges it presents in healthcare settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT264

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT264
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT264 genome assembly,

Gene Summary

Adenine Count

1187747 bp

Thymine Count

1185718 bp

Guanine Count

1584017 bp

Cytosine Count

1580501 bp

Genome Length

5537983 bp

Protein-coding Genes

4975 genes

Non-Coding Genes

388 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nadh-ubiquinone oxidoreductase subunit jSAMEA3538631_02771Not AvailableNegative2862595 - 286314919825.8
nadh dehydrogenase subunit iSAMEA3538631_02772Not AvailableNegative2863161 - 286370320433.7
nadh-ubiquinone oxidoreductase subunit hSAMEA3538631_02773Not AvailableNegative2863718 - 286469536259.1
nadh-ubiquinone oxidoreductase subunit gSAMEA3538631_02774Not AvailableNegative2864692 - 286741899596.2
nadh-ubiquinone oxidoreductase subunit fSAMEA3538631_02775Not AvailableNegative2867451 - 286878849158.0
nadh-ubiquinone oxidoreductase subunit eSAMEA3538631_02776Not AvailableNegative2868785 - 286928518562.0
nadh-ubiquinone oxidoreductase subunit cSAMEA3538631_02777Not AvailableNegative2869288 - 287109669113.9
nadh-ubiquinone oxidoreductase subunit bSAMEA3538631_02778Not AvailableNegative2871183 - 287185725519.8
nadh-ubiquinone/plastoquinone oxidoreductase chain 3SAMEA3538631_02779Not AvailableNegative2871873 - 287223213334.2
lysr family transcriptional regulator lrhaSAMEA3538631_02780Not AvailableNegative2872971 - 287389733468.7

Displaying genes 2921 – 2930 of 5363 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total