Klebsiella pneumoniae strain EuSCAPE_IT313

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT313 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle and is classified as a chemoheterotroph. This organism is capable of existing in various arrangements, including chains, pairs, and singles. It possesses flagella, which facilitate its mobility, and thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. This strain is associated primarily with Homo sapiens but has been identified in a diverse range of hosts, including Gallus gallus, Danio rerio, and various metazoans and plants. Its pathogenicity is significant, as it is linked to a broad spectrum of health effects, such as bacteremia, urinary tract infections, pneumonia, and meningitis, among others. These infections underscore the strain's relevance in clinical settings, particularly concerning its role in severe conditions like sepsis and neonatal sepsis. Notably, Klebsiella pneumoniae strain EuSCAPE_IT313 does not form spores, which may influence its survival and transmission dynamics in host-associated environments. The bacterium's biotic relationship is characterized as free-living, indicating its ability to thrive independently in various ecological niches, despite its pathogenic potential in certain hosts. Overall, the presence and diverse pathogenic capabilities of Klebsiella pneumoniae strain EuSCAPE_IT313 highlight its ecological importance and the need for ongoing monitoring in clinical and environmental contexts to mitigate its impact on human health and associated species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT313

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT313
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT313 genome assembly,

Gene Summary

Adenine Count

1109066 bp

Thymine Count

1105082 bp

Guanine Count

1481764 bp

Cytosine Count

1522699 bp

Genome Length

5218611 bp

Protein-coding Genes

4753 genes

Non-Coding Genes

139 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-galactonate repressor dgorSAMEA3538681_04338Not AvailableNegative4652211 - 465290026037.0
outer membrane protein/protective antigen oma87SAMEA3538681_04339Not AvailableNegative4653130 - 465426342233.3
lipoproteinSAMEA3538681_04340Not AvailableNegative4654260 - 465532138519.8
phosphatase yidaSAMEA3538681_04341Not AvailableNegative4655492 - 465630429544.6
dna gyrase subunit bSAMEA3538681_04342Not AvailableNegative4656506 - 465892090092.3
dna recombination and repair protein recfSAMEA3538681_04343Not AvailableNegative4658949 - 466002240561.6
dna polymerase iii subunit betaSAMEA3538681_04344Not AvailableNegative4660230 - 466133040483.9
chromosomal replication initiator protein dnaaSAMEA3538681_04345Not AvailableNegative4661335 - 466273852369.6
ribonuclease pSAMEA3538681_04346Not AvailablePositive4663549 - 466387512501.4
membrane protein insertaseSAMEA3538681_04347Not AvailablePositive4664099 - 466574561467.5

Displaying genes 4341 – 4350 of 4892 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total