Klebsiella pneumoniae strain EuSCAPE_IT300

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT300 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and chemoheterotroph. This strain typically arranges itself in chains, pairs, and singles, and possesses flagella, which contributes to its mobility. It thrives optimally at 37°C and falls within the mesophilic temperature range. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, and several other species across Metazoa, Viridiplantae, and Aves. It has been identified in a range of health conditions, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Notably, Klebsiella pneumoniae is recognized for its pathogenicity in humans, leading to severe infections such as sepsis and neonatal sepsis, along with complications like liver abscesses and meningitis. Klebsiella pneumoniae strain EuSCAPE_IT300 does not form spores and contains a single replicon within its double-membrane structure. Given its diverse ecological associations and significant pathogenic potential, this strain exemplifies the complex interplay between human health and microbial ecology. Its ability to inhabit a variety of hosts highlights the importance of understanding host-pathogen relationships, particularly in the context of emerging infections and antibiotic resistance. This underscores the need for continuous monitoring and research into Klebsiella species to mitigate their impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT300

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT300
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT300 genome assembly,

Gene Summary

Adenine Count

1317488 bp

Thymine Count

1318117 bp

Guanine Count

1730005 bp

Cytosine Count

1703194 bp

Genome Length

6068804 bp

Protein-coding Genes

5292 genes

Non-Coding Genes

378 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-acetyltransferase gcn5SAMEA3538668_03774Not AvailablePositive3953591 - 395412119447.4
altronate oxidoreductaseSAMEA3538668_03775Not AvailablePositive3954235 - 395568654113.5
n-acetyltransferase gcn5SAMEA3538668_03776Not AvailablePositive3955940 - 395638617228.3
uncharacterised proteinSAMEA3538668_03777Not AvailablePositive3956451 - 39565493737.69
uncharacterised proteinSAMEA3538668_03778Not AvailablePositive3956955 - 395767127082.3
uncharacterised proteinSAMEA3538668_03779Not AvailablePositive3957676 - 39578707550.82
putative hcp1 family type vi secretion system effectorSAMEA3538668_03780Not AvailablePositive3957889 - 395837118397.0
tautomeraseSAMEA3538668_03781Not AvailableNegative3958420 - 395880014515.3
putative carboxymuconolactone decarboxylaseSAMEA3538668_03782Not AvailableNegative3958791 - 395911111586.8
trans-aconitate 2-methyltransferaseSAMEA3538668_03783Not AvailableNegative3959272 - 396003328245.8

Displaying genes 3901 – 3910 of 5670 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total