Klebsiella pneumoniae strain EuSCAPE_IT290

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT290 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and is classified as a chemoheterotroph. This strain is capable of existing in various forms, including chains, pairs, and singles, and is motile, possessing flagella. It thrives optimally at 37°C, placing it within a mesophilic temperature range. This bacterium is primarily host-associated, demonstrating a free-living biotic relationship with a diverse range of hosts, including Homo sapiens, Gallus gallus, Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. The extensive host range indicates its adaptability and potential ecological impact across different environments. Klebsiella pneumoniae strain EuSCAPE_IT290 is notable for its pathogenicity in humans, with associations to various serious health effects. These include bacteremia, urinary tract infections, pneumonia, cystitis, intra-abdominal infections, and more severe conditions such as sepsis and meningitis. The strain's ability to cause infections in different anatomical sites, such as the liver, respiratory tract, and urinary system, underscores its potential as a significant opportunistic pathogen. The presence of this strain in diverse hosts and its capacity to cause a wide range of infections highlight the importance of monitoring Klebsiella pneumoniae in both clinical and environmental contexts. Understanding its behavior and interactions within host organisms is crucial for developing effective strategies to combat its pathogenic effects and prevent outbreaks, emphasizing the need for ongoing research in microbial ecology and infectious disease management.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT290

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT290
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT290 genome assembly,

Gene Summary

Adenine Count

0 bp

Thymine Count

0 bp

Guanine Count

0 bp

Cytosine Count

0 bp

Genome Length

0 bp

Protein-coding Genes

5090 genes

Non-Coding Genes

342 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Concanavalin a-like lectin/glucanase superfamily proteinSAMEA3538658_01221Not AvailablePositive1302232 - 130296325659.7
Hypothetical proteinSAMEA3538658_01222Not AvailablePositive1302960 - 13031637584.69
Tail proteinSAMEA3538658_01223Not AvailablePositive1303193 - 130426939096.9
Tail sheath proteinSAMEA3538658_01224Not AvailablePositive1304408 - 130558042371.2
Putative major tail tube proteinSAMEA3538658_01225Not AvailablePositive1305590 - 130610518585.2
Tail assembly proteinSAMEA3538658_01226Not AvailablePositive1306158 - 130645710671.2
Tail tape measure proteinSAMEA3538658_01227Not AvailablePositive1306584 - 130921193582.4
Putative tail proteinSAMEA3538658_01228Not AvailablePositive1309208 - 130969318120.9
Tail proteinSAMEA3538658_01229Not AvailablePositive1309690 - 131079040956.7
Hypothetical proteinSAMEA3538658_01230Not AvailablePositive1310882 - 13111007964.55

Displaying genes 81 – 90 of 5432 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total