Klebsiella pneumoniae strain EuSCAPE_IT396

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT396 is a Gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic behaviors primarily affecting humans. It is classified as a facultative anaerobe and is capable of thriving in diverse environments, often found in host-associated habitats. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. This strain is known for its mobility, aided by the presence of flagella, and it typically arranges itself in chains, pairs, or as single cells. Klebsiella pneumoniae is a chemoheterotroph, utilizing organic compounds as its energy source. It possesses a complex cellular structure characterized by two membranes and a single replicon. EuSCAPE_IT396 is associated with a wide range of hosts including Homo sapiens (humans), various animals such as Gallus gallus (chickens) and Sus scrofa (pigs), as well as certain plant species (Viridiplantae). Its pathogenic potential is significant, leading to numerous health complications such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The free-living nature of this bacterium highlights its adaptability and ecological versatility. Its ability to infect multiple hosts and cause serious infections underscores its importance in public health and veterinary contexts. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_IT396 can provide insights into its ecological role and the potential risks it poses to both human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT396

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT396
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT396 genome assembly,

Gene Summary

Adenine Count

1221373 bp

Thymine Count

1217878 bp

Guanine Count

1633434 bp

Cytosine Count

1611666 bp

Genome Length

5684351 bp

Protein-coding Genes

5160 genes

Non-Coding Genes

151 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Signal recognition particle proteinSAMEA3538830_01252Not AvailableNegative1342687 - 134405149772.4
Inner membrane protein ypjdSAMEA3538830_01253Not AvailablePositive1344215 - 134500629234.6
Hlyc/corc family transporterSAMEA3538830_01254Not AvailablePositive1345026 - 134631248104.2
Heat shock proteinSAMEA3538830_01255Not AvailableNegative1346432 - 134702221751.9
Dna repair protein recnSAMEA3538830_01256Not AvailablePositive1347147 - 134802532410.0
Dna repair protein recnSAMEA3538830_01257Not AvailablePositive1348112 - 134977361364.2
Outer membrane protein assembly factor bameSAMEA3538830_01258Not AvailablePositive1349921 - 135026212414.0
Rnfh family proteinSAMEA3538830_01259Not AvailableNegative1350329 - 135061910835.1
Type ii toxin-antitoxin system toxin rataSAMEA3538830_01260Not AvailableNegative1350609 - 135104616023.5
Ssra-binding proteinSAMEA3538830_01261Not AvailablePositive1351196 - 135167818240.1

Displaying genes 1 – 10 of 5311 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
SbpCausesPMC10556727
MasldCausesPMC12853991
Urinary tract infectionsCausesPMC12788680
SepticemiaCausesPMC12788680
Abdominal infectionsCausesPMC12788680
Bacterial pneumoniaCausesPMC12788680
Catheter-associated urinary tract infectionCausesPMC2900259
CautiCausesPMC2900259
CystitisCausesPMC4353729
PneumoniaCausesPMC6315841

Displaying health effects 41 – 50 of 53 in total