Klebsiella pneumoniae strain EuSCAPE_IT396

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT396 is a Gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic behaviors primarily affecting humans. It is classified as a facultative anaerobe and is capable of thriving in diverse environments, often found in host-associated habitats. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. This strain is known for its mobility, aided by the presence of flagella, and it typically arranges itself in chains, pairs, or as single cells. Klebsiella pneumoniae is a chemoheterotroph, utilizing organic compounds as its energy source. It possesses a complex cellular structure characterized by two membranes and a single replicon. EuSCAPE_IT396 is associated with a wide range of hosts including Homo sapiens (humans), various animals such as Gallus gallus (chickens) and Sus scrofa (pigs), as well as certain plant species (Viridiplantae). Its pathogenic potential is significant, leading to numerous health complications such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The free-living nature of this bacterium highlights its adaptability and ecological versatility. Its ability to infect multiple hosts and cause serious infections underscores its importance in public health and veterinary contexts. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_IT396 can provide insights into its ecological role and the potential risks it poses to both human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT396

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT396
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT396 genome assembly,

Gene Summary

Adenine Count

1221373 bp

Thymine Count

1217878 bp

Guanine Count

1633434 bp

Cytosine Count

1611666 bp

Genome Length

5684351 bp

Protein-coding Genes

5160 genes

Non-Coding Genes

151 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nad dependent epimerase/dehydratase family proteinSAMEA3538830_02762Not AvailableNegative2967809 - 296925153795.4
low-specificity l-threonine aldolaseSAMEA3538830_02763Not AvailableNegative2969262 - 297026336253.5
pyruvate dehydrogenaseSAMEA3538830_02764Not AvailableNegative2970302 - 297202062017.0
gntr family transcriptional regulatorSAMEA3538830_02765Not AvailablePositive2972172 - 297260615073.1
nadh oxidoreductase hcrSAMEA3538830_02766Not AvailableNegative2972818 - 297378635766.9
hydroxylamine reductaseSAMEA3538830_02767Not AvailableNegative2973797 - 297548261322.8
surface proteinSAMEA3538830_02768Not AvailableNegative2975593 - 297649232504.4
aquaporinSAMEA3538830_02769Not AvailableNegative2976608 - 297730323705.3
old family atp-dependent endonucleaseSAMEA3538830_02770Not AvailablePositive2977723 - 297938163910.5
macrolide-specific efflux protein macaSAMEA3538830_02771Not AvailablePositive2979528 - 298064340725.5

Displaying genes 2771 – 2780 of 5311 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total