Klebsiella pneumoniae strain EuSCAPE_IT370

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT370 is a Gram-negative, rod-shaped bacterium that exhibits a chemoheterotrophic lifestyle. It is facultatively anaerobic, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, characteristic of mesophilic organisms. This strain is notable for its flagella presence, which contributes to its mobility, and its cell arrangement can be observed as chains, pairs, or singles. As a free-living organism, K. pneumoniae strain EuSCAPE_IT370 is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other Metazoa, Viridiplantae, and animal species. This broad host range underscores its ecological versatility. Clinically, K. pneumoniae is associated with a significant array of health effects, particularly in humans. It is known to cause conditions such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain is implicated in serious health complications, including sepsis and neonatal sepsis, as well as other infections like endophthalmitis and liver abscesses. Understanding the pathogenicity of K. pneumoniae strain EuSCAPE_IT370 highlights its role in human health and its potential impact on various hosts. Its ability to adapt to different environments and its association with a wide range of hosts emphasize the importance of monitoring this bacterium in clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT370

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT370
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT370 genome assembly,

Gene Summary

Adenine Count

1256970 bp

Thymine Count

1251736 bp

Guanine Count

1653712 bp

Cytosine Count

1654470 bp

Genome Length

5816888 bp

Protein-coding Genes

5190 genes

Non-Coding Genes

411 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3538777_01495Not AvailablePositive1563903 - 156440918114.8
Hypothetical proteinSAMEA3538777_01496Not AvailablePositive1564406 - 15645194056.57
Ead-like proteinSAMEA3538777_01497Not AvailablePositive1564516 - 156535831249.5
Putative ead/ea22-like proteinSAMEA3538777_01498Not AvailablePositive1565531 - 156617824574.9
Ninb proteinSAMEA3538777_01499Not AvailablePositive1566679 - 156713417424.7
NineSAMEA3538777_01500Not AvailablePositive1567134 - 15673046640.29
Dna junction-specific endonuclease rapSAMEA3538777_01501Not AvailablePositive1567297 - 156793224209.7
Conserved hypothetical bacteriophage proteinSAMEA3538777_01502Not AvailablePositive1567929 - 15680665474.76
Putative hnh endonucleaseSAMEA3538777_01503Not AvailablePositive1568059 - 156858919962.4
Bacteriophage antiterminator protein qSAMEA3538777_01504Not AvailablePositive1568586 - 156927525947.9

Displaying genes 81 – 90 of 5601 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total