Klebsiella pneumoniae strain EuSCAPE_IT180

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT180 is a Gram-negative, rod-shaped bacterium that exhibits a chemoheterotrophic metabolism and is classified as a facultative anaerobe. This strain thrives optimally at 37°C, placing it within the mesophilic temperature range. It is motile and possesses flagella, which contributes to its mobility. This bacterium is commonly found in host-associated environments and demonstrates a free-living biotic relationship. It has a diverse array of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), various Metazoa, Viridiplantae (plants), Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (domestic dogs), Amphibia (amphibians), and Equidae (horses). Klebsiella pneumoniae strain EuSCAPE_IT180 is notable for its pathogenicity in humans, being associated with a wide range of health complications including bacteremia, urinary tract infections, pneumonia, and various types of abscesses. It can also cause severe conditions such as septicemia and neonatal sepsis. The presence of such a versatile organism in multiple hosts highlights its ecological adaptability and potential for cross-species transmission. Understanding the pathogenic traits of Klebsiella pneumoniae, particularly strain EuSCAPE_IT180, is crucial for addressing its impact on public health and developing effective treatment strategies against the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT180

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT180
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT180


Gene Summary

Adenine Count

1230290 bp

Thymine Count

1224915 bp

Guanine Count

1627946 bp

Cytosine Count

1637181 bp

Genome Length

5720332 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
diguanylate cyclaseSAMEA3515209_04273Not AvailablePositive4489024 - 449016343363.1
guanine deaminaseSAMEA3515209_04274Not AvailableNegative4490261 - 449157149395.9
cytosine/purine/uracil/thiamine/allantoin permease family proteinSAMEA3515209_04275Not AvailableNegative4491673 - 449316954425.6
gntr family transcriptional regulatorSAMEA3515209_04276Not AvailablePositive4493314 - 449403026315.6
putative hydantoin racemaseSAMEA3515209_04277Not AvailablePositive4494030 - 449477325694.4
urate catabolism proteinSAMEA3515209_04278Not AvailablePositive4494786 - 449571835623.8
integral membrane proteinSAMEA3515209_04279Not AvailableNegative4495819 - 449658627335.6
arac family transcriptional regulatorSAMEA3515209_04280Not AvailablePositive4496720 - 449748728642.0
histidine phosphataseSAMEA3515209_04281Not AvailablePositive4498085 - 449874424250.0
transcriptional regulator, arac familySAMEA3515209_04282Not AvailableNegative4499235 - 450029038464.8

Displaying genes 4411 – 4420 of 5528 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total