Klebsiella pneumoniae strain EuSCAPE_IT177

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT177 is a gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain is capable of existing in various cell arrangements, including chains, pairs, and singles. It possesses flagella, indicating mobility, and thrives optimally at 37°C, classifying it as mesophilic. EuSCAPE_IT177 is notably associated with multiple hosts, including Homo sapiens and various animal species such as Gallus gallus, Canis lupus familiaris, and Sus scrofa. This wide host range highlights its ecological adaptability. The strain is implicated in numerous health complications, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The pathogenicity of K. pneumoniae in humans is particularly concerning, as it can lead to severe infections like pyogenic liver abscesses and neonatal sepsis. The bacterium is nonsporulating and features a dual membrane structure, typical of gram-negative organisms. Its capacity to exist both freely and in association with hosts suggests a versatile ecological role, allowing it to thrive in diverse environments. Furthermore, the strain's pathogenic potential is significant, contributing to a range of infections that can severely impact human health. Understanding the traits of K. pneumoniae strain EuSCAPE_IT177 is crucial for developing effective strategies to manage infections it causes, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT177

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT177
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT177 genome assembly,

Gene Summary

Adenine Count

1138592 bp

Thymine Count

1139209 bp

Guanine Count

1533501 bp

Cytosine Count

1532801 bp

Genome Length

5344103 bp

Protein-coding Genes

4786 genes

Non-Coding Genes

280 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lyse family transporterSAMEA3515206_00906Not AvailablePositive957480 - 95807021293.8
hydrolaseSAMEA3515206_00907Not AvailableNegative958101 - 95887129110.5
acyl-coa dehydrogenaseSAMEA3515206_00908Not AvailableNegative959050 - 96149489223.6
phosphoheptose isomerase 1SAMEA3515206_00909Not AvailablePositive961734 - 96231520873.0
glutamine amidotransferase class iiSAMEA3515206_00910Not AvailablePositive962390 - 96315728759.5
transpeptidaseSAMEA3515206_00911Not AvailableNegative963128 - 96386828062.7
na(+)-translocating nadh-quinone reductase subunit aSAMEA3515206_00912Not AvailablePositive964280 - 96562348433.8
na(+)-translocating nadh-quinone reductase subunit bSAMEA3515206_00913Not AvailablePositive965627 - 96686545078.7
na(+)-translocating nadh-quinone reductase subunit cSAMEA3515206_00914Not AvailablePositive966858 - 96765228398.2
na(+)-translocating nadh-quinone reductase subunit dSAMEA3515206_00915Not AvailablePositive967645 - 96828323030.9

Displaying genes 1121 – 1130 of 5066 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total