Klebsiella pneumoniae strain EuSCAPE_IT172

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT172 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophy for energy. This strain typically exists in various arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. It thrives optimally at 37°C, within the mesophilic temperature range, and possesses a single replicon and two membranes. EuSCAPE_IT172 is associated with numerous hosts, including Homo sapiens, Gallus gallus, and various other vertebrates and invertebrates, suggesting a broad ecological niche. It is characterized as free-living and exhibits significant pathogenicity in humans, being implicated in a wide range of health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is notably responsible for severe infections like pyogenic liver abscesses and neonatal sepsis. In terms of its ecological impact, Klebsiella pneumoniae's ability to inhabit diverse hosts alongside its pathogenic potential highlights its role in both environmental and clinical settings. The strain's adaptability to various environments and hosts may contribute to its persistence and transmission, emphasizing the importance of monitoring such bacteria in public health contexts. The presence of this bacterium in multiple species underlines its significance in zoonotic disease dynamics and the need for further research into its epidemiology and resistance mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT172

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT172
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT172 genome assembly,

Gene Summary

Adenine Count

1186341 bp

Thymine Count

1179367 bp

Guanine Count

1581438 bp

Cytosine Count

1585056 bp

Genome Length

5532202 bp

Protein-coding Genes

4986 genes

Non-Coding Genes

346 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3515201_00932Not AvailablePositive978896 - 97927914021.8
Outer-membrane spanin componentSAMEA3515201_00933Not AvailablePositive979547 - 97983710382.6
Tail proteinSAMEA3515201_00934Not AvailablePositive979800 - 98023115919.8
Virion morphogenesis proteinSAMEA3515201_00935Not AvailablePositive980224 - 98067017426.2
Hypothetical proteinSAMEA3515201_00936Not AvailableNegative980667 - 98135926276.5
Baseplate assembly protein vSAMEA3515201_00937Not AvailablePositive981454 - 98202620657.2
Baseplate assembly proteinSAMEA3515201_00938Not AvailablePositive982023 - 98238513243.9
Baseplate assembly protein jSAMEA3515201_00939Not AvailablePositive982372 - 98328032702.6
Tail protein iSAMEA3515201_00940Not AvailablePositive983273 - 98387222453.5
Spore coat proteinSAMEA3515201_00941Not AvailablePositive983874 - 986825108679.0

Displaying genes 51 – 60 of 5332 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total