Klebsiella pneumoniae strain EuSCAPE_IT163

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT163 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe that can thrive optimally at 37°C, placing it within the mesophilic temperature range. This bacterium is a chemoheterotroph, utilizing organic compounds for energy. Its cellular arrangement can be observed as chains, pairs, or singles, and it possesses flagella, indicating mobility. K. pneumoniae strain EuSCAPE_IT163 displays a complex biotic relationship, being free-living but primarily associated with various hosts, including Homo sapiens and several animal species such as Gallus gallus, Sus scrofa, and Canis lupus familiaris. It has been implicated in a wide range of health effects, notably causing serious infections like bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is associated with both community-acquired and healthcare-associated infections, presenting a significant health risk in humans and potentially affecting multiple animal species. The presence of only one replicon and two membranes suggests a streamlined genomic structure that is typical of many Enterobacteriaceae. The pathogenicity of this strain underscores its ability to cause severe infections, indicating its potential role in public health concerns. Given its diverse host range and pathogenic capabilities, K. pneumoniae strain EuSCAPE_IT163 exemplifies the ecological versatility of certain bacterial pathogens, highlighting the need for ongoing surveillance and research to manage its spread and impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT163

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT163
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT163 genome assembly,

Gene Summary

Adenine Count

1169026 bp

Thymine Count

1171504 bp

Guanine Count

1586966 bp

Cytosine Count

1547935 bp

Genome Length

5475431 bp

Protein-coding Genes

4986 genes

Non-Coding Genes

132 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Portal proteinSAMEA3515192_00922Not AvailableNegative951661 - 95288746193.0
membrane proteinSAMEA3515192_00923Not AvailableNegative952877 - 9530385438.95
Terminase large subunitSAMEA3515192_00924Not AvailableNegative953035 - 95478665554.7
Terminase small subunitSAMEA3515192_00925Not AvailableNegative954790 - 95528718535.3
uncharacterised proteinSAMEA3515192_00926Not AvailableNegative956429 - 95705523237.2
uncharacterised proteinSAMEA3515192_00927Not AvailableNegative957060 - 95799535604.6
Hypothetical proteinSAMEA3515192_00928Not AvailableNegative958219 - 9584949751.39
EndochitinaseSAMEA3515192_00929Not AvailableNegative958523 - 95913122069.3
Putative holinSAMEA3515192_00930Not AvailableNegative959131 - 95941210289.1
Putative holinSAMEA3515192_00931Not AvailableNegative959399 - 95979413478.4

Displaying genes 21 – 30 of 5118 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total