Klebsiella pneumoniae strain EuSCAPE_IT165

Klebsiella pneumoniae strain EuSCAPE_IT165 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. It thrives optimally at 37°C, placing it within the mesophilic temperature range. This bacterium is predominantly host-associated, exhibiting a free-living biotic relationship, and it has a broad range of potential hosts including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae species. The versatility of its host range highlights its ecological adaptability. Klebsiella pneumoniae strain EuSCAPE_IT165 is associated with numerous health effects, primarily impacting humans. It is known to cause serious infections such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain is implicated in severe conditions including sepsis, neonatal sepsis, and liver abscesses, which underscore its pathogenicity in human hosts. Notably, the strain is non-sporulating and possesses a single replicon and two membranes, characteristics that are common within the Enterobacteriaceae family. The health risks posed by this strain, particularly its ability to cause multiple types of infections, emphasize the need for ongoing monitoring and research into its pathogenic mechanisms and ecological roles in both human and animal hosts. This highlights the importance of understanding the interactions between pathogenic strains and their environments to inform public health strategies.