Klebsiella pneumoniae strain EuSCAPE_IT161

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT161 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of existing in various cell arrangements, including chains, pairs, and singles. It is motile, possessing flagella, which may contribute to its ability to colonize different environments. EuSCAPE_IT161 is primarily associated with hosts, such as Homo sapiens and various other species, including Gallus gallus, Sus scrofa, and Canis lupus familiaris. This strain is of significant clinical relevance, as it is linked to a range of health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The bacterium is non-sporulating and has one replicon and two membranes, characteristics typical of many members of the Enterobacteriaceae family. The optimal growth temperature for EuSCAPE_IT161 is 37°C, placing it within the mesophilic temperature range, which is conducive to growth in warm-blooded hosts. Its free-living biotic relationship suggests that it can thrive independently in various environments, although it is also capable of causing infections in multiple host organisms. The ecological insight from this strain’s profile indicates its adaptability and pathogenic potential across a diverse range of hosts, highlighting the importance of monitoring Klebsiella pneumoniae in both clinical settings and environmental contexts to mitigate its impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT161

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT161
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT161 genome assembly,

Gene Summary

Adenine Count

1195484 bp

Thymine Count

1194550 bp

Guanine Count

1599514 bp

Cytosine Count

1590791 bp

Genome Length

5580339 bp

Protein-coding Genes

5044 genes

Non-Coding Genes

148 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Signal recognition particle proteinSAMEA3515190_01253Not AvailableNegative1342864 - 134422849772.4
Inner membrane protein ypjdSAMEA3515190_01254Not AvailablePositive1344392 - 134518329234.6
Hlyc/corc family transporterSAMEA3515190_01255Not AvailablePositive1345203 - 134648948104.2
Heat shock proteinSAMEA3515190_01256Not AvailableNegative1346609 - 134719921751.9
Dna repair protein recnSAMEA3515190_01257Not AvailablePositive1347324 - 134820232410.0
Dna repair protein recnSAMEA3515190_01258Not AvailablePositive1348289 - 134995061364.2
Outer membrane protein assembly factor bameSAMEA3515190_01259Not AvailablePositive1350098 - 135043912414.0
Rnfh family proteinSAMEA3515190_01260Not AvailableNegative1350506 - 135079610835.1
Type ii toxin-antitoxin system toxin rataSAMEA3515190_01261Not AvailableNegative1350786 - 135122316023.5
Ssra-binding proteinSAMEA3515190_01262Not AvailablePositive1351373 - 135185518240.1

Displaying genes 1 – 10 of 5192 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6315841
Bloodstream infectionsCausesPMC6315841
Surgical site infectionsCausesPMC6315841

Displaying health effects 51 – 53 of 53 in total