Klebsiella pneumoniae strain EuSCAPE_IT161

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT161 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of existing in various cell arrangements, including chains, pairs, and singles. It is motile, possessing flagella, which may contribute to its ability to colonize different environments. EuSCAPE_IT161 is primarily associated with hosts, such as Homo sapiens and various other species, including Gallus gallus, Sus scrofa, and Canis lupus familiaris. This strain is of significant clinical relevance, as it is linked to a range of health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The bacterium is non-sporulating and has one replicon and two membranes, characteristics typical of many members of the Enterobacteriaceae family. The optimal growth temperature for EuSCAPE_IT161 is 37°C, placing it within the mesophilic temperature range, which is conducive to growth in warm-blooded hosts. Its free-living biotic relationship suggests that it can thrive independently in various environments, although it is also capable of causing infections in multiple host organisms. The ecological insight from this strain’s profile indicates its adaptability and pathogenic potential across a diverse range of hosts, highlighting the importance of monitoring Klebsiella pneumoniae in both clinical settings and environmental contexts to mitigate its impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT161

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT161
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT161 genome assembly,

Gene Summary

Adenine Count

1195484 bp

Thymine Count

1194550 bp

Guanine Count

1599514 bp

Cytosine Count

1590791 bp

Genome Length

5580339 bp

Protein-coding Genes

5044 genes

Non-Coding Genes

148 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inner membrane proteinSAMEA3515190_02598Not AvailablePositive2804883 - 280557526102.2
phosphoserine aminotransferaseSAMEA3515190_02599Not AvailablePositive2805764 - 280685239689.5
3-phosphoshikimate 1-carboxyvinyltransferaseSAMEA3515190_02600Not AvailablePositive2806926 - 280820946101.4
cytidylate kinaseSAMEA3515190_02601Not AvailablePositive2808384 - 280906724875.8
30s ribosomal protein s1SAMEA3515190_02602Not AvailablePositive2809201 - 281087461180.5
integration host factor subunit betaSAMEA3515190_02603Not AvailablePositive2811026 - 281131310736.8
putative recombination protein with metallo-hydrolase domainSAMEA3515190_02604Not AvailablePositive2811519 - 281378383952.6
lipid a export atp-binding/permease msbaSAMEA3515190_02605Not AvailablePositive2813820 - 281556864527.7
tetraacyldisaccharide 4'-kinaseSAMEA3515190_02606Not AvailablePositive2815565 - 281654535644.4
uncharacterized protein conserved in bacteriaSAMEA3515190_02607Not AvailablePositive2816600 - 281782947460.1

Displaying genes 2651 – 2660 of 5192 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total