Klebsiella pneumoniae strain EuSCAPE_IT151

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT151 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism. It is classified as a chemoheterotroph, utilizing organic compounds for energy. This strain is capable of mobility, possessing flagella, and typically arranges itself in chains, pairs, or as singles. Its optimal growth temperature is 37°C, which aligns with its classification as mesophilic. EuSCAPE_IT151 is known to be associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans, indicating its ability to inhabit diverse biological environments. Its pathogenic potential in humans is significant, as it is associated with a range of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The bacterium is nonsporulating and has a single replicon with two membranes. The presence of Klebsiella pneumoniae in various hosts suggests an ecological versatility that may contribute to its survival and transmission. Its ability to cause infections across different species underscores its role as a significant opportunistic pathogen. In a broader biological context, the pathogenicity of EuSCAPE_IT151 exemplifies the complexities of host-pathogen interactions and the potential for zoonotic transmission, highlighting the importance of monitoring and understanding such microbial strains in both clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT151

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT151
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT151 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4924 genes

Non-Coding Genes

361 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alcohol dehydrogenaseSAMEA3515180_01199Not AvailableNegative1299291 - 130030135292.5
inorganic diphosphataseSAMEA3515180_01200Not AvailablePositive1300554 - 130115321838.2
putative marr family regulatory proteinSAMEA3515180_01201Not AvailablePositive1301334 - 130228734817.6
putative transporter atp-binding componentSAMEA3515180_01202Not AvailableNegative1302324 - 130403962851.4
putative glycosyltransferaseSAMEA3515180_01203Not AvailableNegative1304397 - 130508326733.3
putative glycosyltransferaseSAMEA3515180_01204Not AvailableNegative1305080 - 130577526510.4
nad-dependent malic enzymeSAMEA3515180_01205Not AvailableNegative1305959 - 130765662775.4
30s ribosomal subunit s22SAMEA3515180_01206Not AvailableNegative1307838 - 13079785279.38
metallo-beta-lactamase superfamily proteinSAMEA3515180_01207Not AvailableNegative1308156 - 130900730870.0
lysr family transcriptional regulatorSAMEA3515180_01208Not AvailablePositive1309121 - 131001432422.3

Displaying genes 1441 – 1450 of 5284 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total