Klebsiella pneumoniae strain EuSCAPE_IT149

Klebsiella pneumoniae strain EuSCAPE_IT149 is a gram-negative, rod-shaped bacterium that exhibits a range of pathogenic effects in humans. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is chemoheterotrophic, deriving its energy from organic compounds, and possesses mobility due to the presence of flagella. In terms of habitat, EuSCAPE_IT149 is host-associated, primarily affecting Homo sapiens, but also found in various other hosts, including Gallus gallus (chickens), Danio rerio (zebrafish), and several mammals. Its biotic relationships are characterized as free-living, indicating its ability to exist independently in the environment while maintaining pathogenic potential in hosts. EuSCAPE_IT149 is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the average human body temperature. It is notable for its health effects, which include a range of serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is nonsporulating and has a single circular replicon, characteristic of many bacteria within this genus. The diverse host range and the potential for serious health impacts highlight the ecological adaptability and pathogenicity of Klebsiella pneumoniae strain EuSCAPE_IT149. Understanding its interactions with various hosts is crucial for developing effective strategies to manage the infections it causes, particularly in clinical settings where multi-drug resistance is a growing concern.