Klebsiella pneumoniae strain EuSCAPE_IT136

Klebsiella pneumoniae strain EuSCAPE_IT136 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans and various other hosts, including mammals and birds. This strain is facultative anaerobic, allowing it to thrive in diverse environments by utilizing oxygen when available while also being capable of anaerobic respiration. It is a chemoheterotroph, deriving energy from organic compounds. EuSCAPE_IT136 is characterized by its cellular arrangement, which can occur in chains, pairs, or as single cells. The bacterium possesses flagella, granting it mobility, and it typically grows optimally at 37°C, fitting within a mesophilic temperature range. It has a unique cellular structure with two membranes and a single replicon. Pathologically, K. pneumoniae strain EuSCAPE_IT136 is associated with a wide range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and other systemic infections. It is particularly notable for causes of neonatal sepsis and various intra-abdominal infections. The strain's ability to infect a diverse host range, including Homo sapiens, Gallus gallus, and several other vertebrates, underscores its ecological adaptability and potential for zoonotic transmission. The nonsporulating nature of EuSCAPE_IT136 suggests that its survival and persistence in the environment may rely on its ability to form biofilms or other protective structures. This adaptability is crucial for its role in both human health and disease, illustrating the complex interactions between pathogenic bacteria and their hosts in various ecological niches.