Klebsiella pneumoniae strain EuSCAPE_IT130

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT130 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. It primarily serves as a chemoheterotroph, utilizing organic compounds as energy sources. The bacterium is motile, possessing flagella, and typically forms arrangements in chains, pairs, or singles. This strain is mesophilic, with an optimal growth temperature of 37°C, which corresponds with the body temperature of its primary hosts, including Homo sapiens and various other organisms such as Gallus gallus (chickens), Danio rerio (zebrafish), and Sus scrofa (pigs). Its ability to inhabit a broad range of hosts indicates a versatile ecological niche. Klebsiella pneumoniae strain EuSCAPE_IT130 is associated with a number of health-related issues in its hosts, particularly in humans, where it is linked to conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. This demonstrates its pathogenicity and highlights the strain's role in significant clinical illnesses, particularly in immunocompromised individuals. The strain's free-living nature and its potential for causing serious infections underscore its ecological and medical importance. By thriving in diverse habitats and infecting various species, Klebsiella pneumoniae strain EuSCAPE_IT130 illustrates the complex interactions between microorganisms and their hosts, emphasizing the need for ongoing surveillance and research to address its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT130

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT130
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT130 genome assembly,

Gene Summary

Adenine Count

1221832 bp

Thymine Count

1223609 bp

Guanine Count

1636356 bp

Cytosine Count

1617271 bp

Genome Length

5699068 bp

Protein-coding Genes

5141 genes

Non-Coding Genes

393 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiol:disulfide interchange protein dsbgSAMEA3515159_01427Not AvailableNegative1481805 - 148255427923.2
alkyl hydroperoxide reductase protein cSAMEA3515159_01428Not AvailablePositive1482966 - 148352920764.5
alkyl hydroperoxide reductase protein fSAMEA3515159_01429Not AvailablePositive1483717 - 148528256021.9
universal stress protein gSAMEA3515159_01430Not AvailableNegative1485359 - 148578715953.4
regulator of nucleoside diphosphate kinaseSAMEA3515159_01431Not AvailableNegative1485974 - 148638414868.8
ribonuclease iSAMEA3515159_01432Not AvailableNegative1486563 - 148736029155.8
c4-dicarboxylate transporter dcucSAMEA3515159_01433Not AvailableNegative1487453 - 148882647948.8
antimicrobial peptide resistance and lipid a acylation pagpSAMEA3515159_01434Not AvailablePositive1489165 - 148968319768.9
cold shock protein cspeSAMEA3515159_01435Not AvailablePositive1489878 - 14900877449.81
protein crcbSAMEA3515159_01436Not AvailableNegative1490155 - 149053813665.0

Displaying genes 1641 – 1650 of 5534 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total