Klebsiella pneumoniae strain EuSCAPE_IT130

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT130 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. It primarily serves as a chemoheterotroph, utilizing organic compounds as energy sources. The bacterium is motile, possessing flagella, and typically forms arrangements in chains, pairs, or singles. This strain is mesophilic, with an optimal growth temperature of 37°C, which corresponds with the body temperature of its primary hosts, including Homo sapiens and various other organisms such as Gallus gallus (chickens), Danio rerio (zebrafish), and Sus scrofa (pigs). Its ability to inhabit a broad range of hosts indicates a versatile ecological niche. Klebsiella pneumoniae strain EuSCAPE_IT130 is associated with a number of health-related issues in its hosts, particularly in humans, where it is linked to conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. This demonstrates its pathogenicity and highlights the strain's role in significant clinical illnesses, particularly in immunocompromised individuals. The strain's free-living nature and its potential for causing serious infections underscore its ecological and medical importance. By thriving in diverse habitats and infecting various species, Klebsiella pneumoniae strain EuSCAPE_IT130 illustrates the complex interactions between microorganisms and their hosts, emphasizing the need for ongoing surveillance and research to address its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT130

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT130
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT130 genome assembly,

Gene Summary

Adenine Count

1221832 bp

Thymine Count

1223609 bp

Guanine Count

1636356 bp

Cytosine Count

1617271 bp

Genome Length

5699068 bp

Protein-coding Genes

5141 genes

Non-Coding Genes

393 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
methionyl-trna synthetaseSAMEA3515159_00937Not AvailablePositive953751 - 95579376502.1
protein of uncharacterised function (duf1456)SAMEA3515159_00938Not AvailableNegative955908 - 95637817929.6
response regulatory protein yehtSAMEA3515159_00939Not AvailableNegative956426 - 95714527517.6
autolysin sensor kinaseSAMEA3515159_00940Not AvailableNegative957139 - 95886363346.9
membrane proteinSAMEA3515159_00941Not AvailablePositive959057 - 9591703738.93
osmoprotectant abc transporter inner membrane protein yehwSAMEA3515159_00942Not AvailableNegative959145 - 95988225647.0
osmoprotectant abc transporter atp-binding subunit yehxSAMEA3515159_00943Not AvailableNegative959866 - 96081335069.7
osmoprotectant abc transporter permease protein yehySAMEA3515159_00944Not AvailableNegative960806 - 96196341076.9
glycine betaine/choline abc transporter membrane proteinSAMEA3515159_00945Not AvailableNegative961971 - 96288832873.3
beta-d-glucoside glucohydrolaseSAMEA3515159_00946Not AvailableNegative963025 - 96532283403.6

Displaying genes 1211 – 1220 of 5534 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total