Klebsiella pneumoniae strain EuSCAPE_IT127

Klebsiella pneumoniae strain EuSCAPE_IT127 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain exhibits a variety of cell arrangements, including chains, pairs, and singles, and possesses flagella, which contribute to its mobility. EuSCAPE_IT127 thrives at an optimal temperature of 37°C, classifying it as mesophilic. This bacterium is notably host-associated, with a diverse range of hosts including Homo sapiens, various avian species (Gallus gallus, Phasianidae, Aves), and other vertebrates such as Danio rerio, Sus scrofa, Canis lupus familiaris, and Equidae, among others. Its ability to inhabit multiple hosts indicates a flexible ecological niche, which may facilitate its spread in various environments. Klebsiella pneumoniae strain EuSCAPE_IT127 is associated with significant health impacts in humans, including bacteremia, urinary tract infections, pneumonia, intra-abdominal infections, and sepsis. The strain's pathogenicity is a serious concern, particularly in healthcare settings where it can lead to severe infections such as neonatal sepsis and pneumonia in mink. The presence of a single replicon and a double membrane structure is consistent with the characteristics of many Gram-negative bacteria, which may influence its interactions with host immune systems. Understanding the ecological roles and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_IT127 can provide insights into bacterial behavior in host-associated environments and inform strategies for managing infections it causes.