Klebsiella pneumoniae strain EuSCAPE_IT117

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT117 is a gram-negative, mesophilic, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain exhibits a diverse cell arrangement, occurring in chains, pairs, and singles, and possesses mobility due to the presence of flagella. Its optimal growth temperature is 37°C, making it well-suited for growth in human-associated environments. This strain is primarily associated with a range of hosts, including Homo sapiens and various animal species such as Gallus gallus (chickens), Canis lupus familiaris (domestic dogs), and Danio rerio (zebrafish), among others. The biotic relationship of EuSCAPE_IT117 is classified as free-living, indicating its potential to exist independently in various ecological niches. Klebsiella pneumoniae strain EuSCAPE_IT117 is implicated in numerous health effects, particularly in humans. It is known to cause severe infections, including bacteremia, urinary tract infections, pneumonia, and meningitis. The strain's pathogenicity is significant, leading to conditions such as sepsis and pyogenic liver abscesses, highlighting its role as a serious human pathogen. The presence of this strain in diverse hosts suggests ecological versatility and adaptability, which may contribute to its spread and persistence in various environments. Its capacity to cause infections in both humans and animals underscores the importance of monitoring and controlling its presence in healthcare settings to mitigate the risk of transmission and infection.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT117

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT117
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT117 genome assembly,

Gene Summary

Adenine Count

1146698 bp

Thymine Count

1149254 bp

Guanine Count

1531694 bp

Cytosine Count

1541458 bp

Genome Length

5369104 bp

Protein-coding Genes

4840 genes

Non-Coding Genes

244 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative hcp1 family type vi secretion system effectorSAMEA3515146_00069Not AvailablePositive64487 - 6496918382.0
tautomeraseSAMEA3515146_00070Not AvailableNegative65018 - 6539814496.2
putative carboxymuconolactone decarboxylaseSAMEA3515146_00071Not AvailableNegative65389 - 6570911552.8
trans-aconitate 2-methyltransferaseSAMEA3515146_00072Not AvailableNegative65870 - 6663128189.8
uncharacterised proteinSAMEA3515146_00073Not AvailableNegative66840 - 6713011103.4
transporterSAMEA3515146_00074Not AvailableNegative67359 - 6854641719.9
prolyl endopeptidaseSAMEA3515146_00075Not AvailableNegative68702 - 6912415396.2
major facilitator family transporterSAMEA3515146_00076Not AvailablePositive69332 - 7048940240.4
lysr family transcriptional regulatorSAMEA3515146_00077Not AvailableNegative70486 - 7133130471.0
enoyl-[acyl-carrier-protein] reductaseSAMEA3515146_00078Not AvailablePositive71421 - 7247936874.2

Displaying genes 261 – 270 of 5084 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total