Klebsiella pneumoniae strain EuSCAPE_IT112

Klebsiella pneumoniae strain EuSCAPE_IT112 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments, exhibiting a facultative anaerobic metabolism as a chemoheterotroph. This organism displays mobility, facilitated by the presence of flagella, and typically arranges itself in chains, pairs, or singles. With an optimal growth temperature of 37°C, it falls within the mesophilic temperature range. This strain is notable for its pathogenicity in humans, being associated with various health complications, including bacteremia, urinary tract infections, pneumonia, cystitis, intra-abdominal infections, and liver abscesses, among others. Its ability to cause a wide range of infections underscores its significance as a clinical pathogen. Klebsiella pneumoniae strain EuSCAPE_IT112 has a biotic relationship characterized as free-living, yet it is known to infect a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other vertebrate species, such as Danio rerio (zebrafish), Ovis aries (sheep), and Canis lupus familiaris (domestic dogs). This broad host range indicates its ecological versatility and potential for interspecies transmission. The organism contains a single replicon and is nonsporulating, with a double membrane structure typical of Gram-negative bacteria. Its capacity to cause significant health issues highlights not only its pathogenic potential but also raises concerns regarding its role in public health and the importance of monitoring its prevalence in both human and animal populations.