Klebsiella pneumoniae strain EuSCAPE_IT258

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT258 is a facultative anaerobic, gram-negative bacterium characterized by its rod shape and the presence of flagella, which contributes to its mobility. This strain is a chemoheterotroph, utilizing organic compounds for energy. It typically thrives at an optimal temperature of 37°C, falling within the mesophilic range, and can be found in various arrangements, including chains, pairs, and singles. K. pneumoniae EuSCAPE_IT258 is notably pathogenic to humans, associated with a variety of health complications including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. It can also affect a range of hosts, including domesticated animals like Gallus gallus (chickens) and Sus scrofa (pigs), as well as various species within the Metazoa and Viridiplantae kingdoms. This broad host range indicates its ecological versatility and adaptability. The strain is free-living and possesses a single replicon and two membranes, typical of Gram-negative bacteria, which may influence its interactions with host organisms and the environment. Understanding the pathogenicity and environmental adaptability of Klebsiella pneumoniae strain EuSCAPE_IT258 can offer insights into its role in clinical settings and the potential for zoonotic transmission, highlighting the importance of monitoring this bacterium in both human health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT258

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT258
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT258 genome assembly,

Gene Summary

Adenine Count

1229153 bp

Thymine Count

1225238 bp

Guanine Count

1634659 bp

Cytosine Count

1630417 bp

Genome Length

5719467 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
histidine abc transporterSAMEA3538625_00227Not AvailableNegative274795 - 27551126650.0
histidine abc transporterSAMEA3538625_00228Not AvailableNegative275508 - 27619424540.7
histidine abc transporterSAMEA3538625_00229Not AvailableNegative276259 - 27704128548.2
lysine/arginine/ornithine abc transporter substrate-binding periplasmic proteinSAMEA3538625_00230Not AvailableNegative277309 - 27809128125.4
3-polyprenyl-4-hydroxybenzoate carboxy-lyase ubixSAMEA3538625_00231Not AvailableNegative278374 - 27894320812.4
amidophosphoribosyltransferaseSAMEA3538625_00232Not AvailableNegative279079 - 28059656524.4
colicin v production proteinSAMEA3538625_00233Not AvailableNegative280630 - 28111818101.2
sporulation domain-containing proteinSAMEA3538625_00234Not AvailableNegative281335 - 28202424030.8
dihydrofolate synthaseSAMEA3538625_00235Not AvailableNegative282014 - 28328245073.1
acetyl-coa carboxylase subunit betaSAMEA3538625_00236Not AvailableNegative283358 - 28434135729.7

Displaying genes 581 – 590 of 5546 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total