Klebsiella pneumoniae strain EuSCAPE_IT258

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT258 is a facultative anaerobic, gram-negative bacterium characterized by its rod shape and the presence of flagella, which contributes to its mobility. This strain is a chemoheterotroph, utilizing organic compounds for energy. It typically thrives at an optimal temperature of 37°C, falling within the mesophilic range, and can be found in various arrangements, including chains, pairs, and singles. K. pneumoniae EuSCAPE_IT258 is notably pathogenic to humans, associated with a variety of health complications including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. It can also affect a range of hosts, including domesticated animals like Gallus gallus (chickens) and Sus scrofa (pigs), as well as various species within the Metazoa and Viridiplantae kingdoms. This broad host range indicates its ecological versatility and adaptability. The strain is free-living and possesses a single replicon and two membranes, typical of Gram-negative bacteria, which may influence its interactions with host organisms and the environment. Understanding the pathogenicity and environmental adaptability of Klebsiella pneumoniae strain EuSCAPE_IT258 can offer insights into its role in clinical settings and the potential for zoonotic transmission, highlighting the importance of monitoring this bacterium in both human health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT258

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT258
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT258 genome assembly,

Gene Summary

Adenine Count

1229153 bp

Thymine Count

1225238 bp

Guanine Count

1634659 bp

Cytosine Count

1630417 bp

Genome Length

5719467 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipoprotein ycebSAMEA3538625_01248Not AvailableNegative1311333 - 131189320282.6
multidrug resistance protein mdthSAMEA3538625_01249Not AvailableNegative1312007 - 131321543890.2
ribosomal-protein-s5p-alanine acetyltransferaseSAMEA3538625_01250Not AvailablePositive1313406 - 131402923908.7
g20.3SAMEA3538625_01251Not AvailablePositive1314039 - 131469224256.9
oxidoreductase family, nad-bindingSAMEA3538625_01252Not AvailablePositive1314696 - 131561934201.9
putative virulence factorSAMEA3538625_01253Not AvailablePositive1315731 - 131726655358.1
putative permease of the major facilitator superfamilySAMEA3538625_01254Not AvailableNegative1317319 - 131853341974.9
lysr family transcriptional regulatorSAMEA3538625_01255Not AvailablePositive1318643 - 131957834785.3
ribonuclease, rne/rng familySAMEA3538625_01256Not AvailableNegative1319617 - 1322850119196.0
ribosomal large subunit pseudouridine synthase cSAMEA3538625_01257Not AvailablePositive1323508 - 132450337266.1

Displaying genes 1501 – 1510 of 5546 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total