Klebsiella pneumoniae strain EuSCAPE_IT250

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT250 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in both aerobic and anaerobic environments. It is classified as a chemoheterotroph, utilizing organic compounds as its energy source. This strain is capable of mobility due to the presence of flagella and typically exists in various arrangements, including chains, pairs, and singles. The optimal temperature for growth of EuSCAPE_IT250 is 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and features a double membrane structure, characteristic of Gram-negative bacteria. This strain is known for its free-living biotic relationship and has a diverse range of hosts, including Homo sapiens, various birds, fish, mammals, and amphibians. Klebsiella pneumoniae strain EuSCAPE_IT250 is associated with several serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity underscores its significance in clinical microbiology. The strain is nonsporulating, which may influence its survival and transmission in various environments. An ecological insight from the data indicates that Klebsiella pneumoniae strain EuSCAPE_IT250 has a broad host range, suggesting its adaptability and potential for cross-species transmission. This adaptability may also contribute to its persistent role in human health as a pathogen, as it can thrive in diverse biological settings, including hospital environments where infection control is critical. Understanding its traits can aid in developing strategies to manage its impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT250

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT250
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT250 genome assembly,

Gene Summary

Adenine Count

1231762 bp

Thymine Count

1227960 bp

Guanine Count

1635826 bp

Cytosine Count

1633831 bp

Genome Length

5729379 bp

Protein-coding Genes

5148 genes

Non-Coding Genes

408 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Terminase large subunitSAMEA3538617_00391Not AvailableNegative441439 - 44291454920.5
Terminase small subunitSAMEA3538617_00392Not AvailableNegative442911 - 44349522478.4
Hypothetical proteinSAMEA3538617_00393Not AvailableNegative443573 - 44383010011.8
Trna-leu;Not AvailableNot AvailablePositive443685 - 443771Not Available
Hypothetical proteinSAMEA3538617_00394Not AvailableNegative443905 - 44424312606.2
Hypothetical proteinSAMEA3538617_00395Not AvailableNegative444243 - 4444829069.38
Valyl-trna synthetaseSAMEA3538617_00396Not AvailableNegative444475 - 44514324681.9
Hypothetical proteinSAMEA3538617_00397Not AvailableNegative445140 - 4453527789.18
Hypothetical proteinSAMEA3538617_00398Not AvailableNegative445353 - 4455236375.24
Bcepny3gp60SAMEA3538617_00399Not AvailableNegative445523 - 44626628046.2

Displaying genes 31 – 40 of 5556 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total