Klebsiella pneumoniae strain EuSCAPE_IT256

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT256 is a gram-negative, rod-shaped bacterium that is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is chemoheterotrophic, utilizing organic compounds for energy, and exhibits mobility due to the presence of flagella. It typically exists in various arrangements, including chains, pairs, and singles. EuSCAPE_IT256 has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary host, Homo sapiens. This strain is associated with a wide array of hosts, including domestic animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as various metazoans and plants. The pathogenicity of K. pneumoniae EuSCAPE_IT256 is significant, as it is known to cause a variety of serious health conditions in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to infect multiple hosts suggests a versatile ecological role, allowing it to thrive in diverse environments, including those associated with both humans and animals. The presence of this strain in various hosts highlights its potential as an opportunistic pathogen, especially in immunocompromised individuals. Its free-living nature, coupled with its capacity to cause a range of infections, emphasizes the importance of monitoring its spread and understanding its interactions within different ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT256

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT256
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT256 genome assembly,

Gene Summary

Adenine Count

1206076 bp

Thymine Count

1214822 bp

Guanine Count

1629429 bp

Cytosine Count

1602341 bp

Genome Length

5652668 bp

Protein-coding Genes

5086 genes

Non-Coding Genes

378 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein of uncharacterised function (duf1451)SAMEA3538623_01314Not AvailablePositive1389539 - 139002418762.1
filamentous hemagglutininSAMEA3538623_01315Not AvailableNegative1390070 - 139186361196.6
putative hemolysin activator hlybSAMEA3538623_01316Not AvailableNegative1391929 - 139359962127.0
glutamate aspartate transport atp-binding protein gltlSAMEA3538623_01317Not AvailableNegative1393973 - 139469826588.6
glutamate aspartate transport system permease protein gltkSAMEA3538623_01318Not AvailableNegative1394698 - 139537224862.2
glutamate aspartate transport system permease protein gltjSAMEA3538623_01319Not AvailableNegative1395372 - 139611227488.1
glutamate and aspartate transporter subunitSAMEA3538623_01320Not AvailableNegative1396277 - 139718833474.2
apolipoprotein n-acyltransferaseSAMEA3538623_01321Not AvailableNegative1397543 - 139908157619.9
magnesium and cobalt efflux protein corcSAMEA3538623_01322Not AvailableNegative1399207 - 140015435964.4
metal-dependent hydrolase ybeySAMEA3538623_01323Not AvailableNegative1400233 - 140070617684.9

Displaying genes 1601 – 1610 of 5464 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total