Klebsiella pneumoniae strain EuSCAPE_IT247

Klebsiella pneumoniae strain EuSCAPE_IT247 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is characterized by its mobility, with flagella present, and typically exists in various arrangements, including chains, pairs, and singles. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for colonization in warm-blooded hosts. The strain has a free-living biotic relationship, predominantly associated with a wide range of hosts including Homo sapiens (humans), Gallus gallus (chickens), and various other mammals, birds, and plants. Its pathogenicity is notably significant in humans, where it can cause a variety of severe health conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. The health impacts extend to neonatal populations, where it can lead to conditions like early onset neonatal sepsis. Klebsiella pneumoniae strain EuSCAPE_IT247 possesses a single replicon and is surrounded by two membranes, typical of Gram-negative bacteria. This structural characteristic supports its ability to evade certain host immune responses and contributes to its pathogenicity. Ecologically, the presence of Klebsiella pneumoniae in diverse environments, including animal and plant hosts, underscores its adaptability and potential role in both health and disease. Understanding its interactions within various ecosystems could provide insights into its transmission dynamics and the emergence of antibiotic-resistant strains, which is a growing concern in public health.