Klebsiella pneumoniae strain EuSCAPE_IT242

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT242 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is characterized by its mobility, facilitated by the presence of flagella, and it typically forms chains, pairs, or singles. It thrives optimally at a temperature of 37°C, placing it within the mesophilic range. This bacterium is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and other metazoans, as well as certain plants and aquatic species. Its pathogenic profile is significant, as it is known to cause numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and liver abscesses, among others. These infections can lead to severe conditions such as sepsis and neonatal sepsis, highlighting the strain's potential impact on human health. Despite its pathogenic capabilities, K. pneumoniae strain EuSCAPE_IT242 can also exhibit free-living characteristics, indicating a versatile ecological role. This dual nature underscores its adaptability within various environments, which may facilitate its transmission and persistence in both clinical and natural settings. Understanding the traits and behaviors of this strain is crucial for addressing its health implications and for developing effective management strategies in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT242

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT242
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT242 genome assembly,

Gene Summary

Adenine Count

1187058 bp

Thymine Count

1188094 bp

Guanine Count

1604686 bp

Cytosine Count

1573908 bp

Genome Length

5553746 bp

Protein-coding Genes

4995 genes

Non-Coding Genes

386 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rnase iii inhibitorSAMEA3538609_00705Not AvailablePositive767818 - 76834518429.1
tetr family transcriptional regulatorSAMEA3538609_00706Not AvailablePositive768412 - 76900521593.8
glucans biosynthesis proteinSAMEA3538609_00707Not AvailableNegative769040 - 77020044252.1
glucans biosynthesis protein gSAMEA3538609_00708Not AvailablePositive770452 - 77200558572.5
glucans biosynthesis glucosyltransferase hSAMEA3538609_00709Not AvailablePositive771998 - 77452696053.6
outer membrane lipoproteinSAMEA3538609_00710Not AvailablePositive774593 - 7748208316.15
acidic protein msybSAMEA3538609_00711Not AvailableNegative774821 - 77520714763.3
multidrug-efflux transporter, major facilitator superfamily (mfs)SAMEA3538609_00712Not AvailableNegative775299 - 77652543715.7
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3538609_00713Not AvailableNegative776697 - 77761735528.0
putative rhodanese-related sulfurtransferaseSAMEA3538609_00714Not AvailablePositive777823 - 77888740237.0

Displaying genes 951 – 960 of 5381 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total