Klebsiella pneumoniae strain EuSCAPE_IT242

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT242 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is characterized by its mobility, facilitated by the presence of flagella, and it typically forms chains, pairs, or singles. It thrives optimally at a temperature of 37°C, placing it within the mesophilic range. This bacterium is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and other metazoans, as well as certain plants and aquatic species. Its pathogenic profile is significant, as it is known to cause numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and liver abscesses, among others. These infections can lead to severe conditions such as sepsis and neonatal sepsis, highlighting the strain's potential impact on human health. Despite its pathogenic capabilities, K. pneumoniae strain EuSCAPE_IT242 can also exhibit free-living characteristics, indicating a versatile ecological role. This dual nature underscores its adaptability within various environments, which may facilitate its transmission and persistence in both clinical and natural settings. Understanding the traits and behaviors of this strain is crucial for addressing its health implications and for developing effective management strategies in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT242

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT242
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT242 genome assembly,

Gene Summary

Adenine Count

1187058 bp

Thymine Count

1188094 bp

Guanine Count

1604686 bp

Cytosine Count

1573908 bp

Genome Length

5553746 bp

Protein-coding Genes

4995 genes

Non-Coding Genes

386 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
maltose/maltodextrin abc transporterSAMEA3538609_01346Not AvailablePositive1429525 - 143083248820.3
maltose/maltodextrin abc transporterSAMEA3538609_01347Not AvailablePositive1430843 - 143169431322.1
galactosidaseSAMEA3538609_01348Not AvailablePositive1431699 - 143290144802.9
beta-galactosidaseSAMEA3538609_01349Not AvailablePositive1432933 - 143499077560.9
pts system glucose-specific transporter subunit iibcSAMEA3538609_01350Not AvailablePositive1435055 - 143536911392.7
maltoporinSAMEA3538609_01351Not AvailableNegative1435506 - 143677746790.2
lac operon transcriptional repressorSAMEA3538609_01352Not AvailablePositive1437048 - 143811838800.2
50s ribosomal protein l31SAMEA3538609_01353Not AvailablePositive1438234 - 14384979944.69
50s ribosomal protein l36SAMEA3538609_01354Not AvailablePositive1438497 - 14386375465.88
gnat family acetyltransferaseSAMEA3538609_01355Not AvailableNegative1438634 - 143933226579.4

Displaying genes 1591 – 1600 of 5381 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total