Klebsiella pneumoniae strain EuSCAPE_IT234

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT234 is a Gram-negative, rod-shaped bacterium classified as a chemoheterotroph and a facultative anaerobe. This strain typically exists in host-associated environments and is capable of forming chains, pairs, or existing as singles. It possesses flagella, allowing for mobility, and is mesophilic, with an optimal growth temperature of 37°C. This strain has significant pathogenic potential, particularly in humans, where it can cause a variety of severe health issues including bacteremia, pneumonia, urinary tract infections, and intra-abdominal infections. Other notable health effects include liver abscesses, meningitis, and sepsis, among others. The diverse range of hosts for Klebsiella pneumoniae strain EuSCAPE_IT234 extends beyond humans to include various species such as Gallus gallus (chickens), Danio rerio (zebrafish), and Canis lupus familiaris (domestic dogs), indicating its adaptability to different biological environments. The bacterium's ability to thrive in various host species may facilitate its persistence in the environment and contribute to its role as a significant opportunistic pathogen. The presence of this strain in multiple hosts suggests a complex ecological relationship, where it can exploit different niches and possibly transfer between species, enhancing its survival and pathogenic capabilities. Understanding the traits and behaviors of Klebsiella pneumoniae strain EuSCAPE_IT234 is essential for developing effective strategies to manage infections it causes, especially in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT234

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT234
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT234 genome assembly,

Gene Summary

Adenine Count

1207242 bp

Thymine Count

1200034 bp

Guanine Count

1606874 bp

Cytosine Count

1602927 bp

Genome Length

5617077 bp

Protein-coding Genes

5049 genes

Non-Coding Genes

396 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter, periplasmic substrate-binding protein ynjbSAMEA3538601_03581Not AvailableNegative3751523 - 375270143212.4
carboxymuconolactone decarboxylase family proteinSAMEA3538601_03582Not AvailableNegative3752704 - 375326420757.3
alkaline phosphataseSAMEA3538601_03583Not AvailableNegative3753261 - 375397125456.6
deda family inner membrane protein ydjxSAMEA3538601_03584Not AvailableNegative3753958 - 375461423739.5
exodeoxyribonuclease iiiSAMEA3538601_03585Not AvailableNegative3754828 - 375563430899.6
succinylornithine transaminaseSAMEA3538601_03586Not AvailablePositive3756073 - 375729343493.0
arginine n-succinyltransferaseSAMEA3538601_03587Not AvailablePositive3757290 - 375832438362.0
succinylglutamic semialdehyde dehydrogenaseSAMEA3538601_03588Not AvailablePositive3758321 - 375979952171.2
succinylarginine dihydrolaseSAMEA3538601_03589Not AvailablePositive3759796 - 376112148440.4
succinylglutamate desuccinylaseSAMEA3538601_03590Not AvailablePositive3761131 - 376209636514.9

Displaying genes 3751 – 3760 of 5445 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total