Klebsiella pneumoniae strain EuSCAPE_IT233

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT233 is a Gram-negative, rod-shaped bacterium recognized for its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain is capable of mobility, supported by the presence of flagella, and typically exists in chains, pairs, or as singles. It thrives optimally at 37°C, categorizing it as mesophilic. EuSCAPE_IT233 is predominantly associated with a variety of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and vertebrates, demonstrating a wide-ranging ecological adaptability. Its biotic relationship is classified as free-living, indicating its ability to inhabit diverse environments while relying on organic compounds for energy. This strain is notably pathogenic to humans, associated with numerous health complications such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Its capacity to cause severe conditions like meningitis, sepsis, and liver abscesses underscores its medical significance. Klebsiella pneumoniae strain EuSCAPE_IT233’s ability to thrive in various biological settings and its extensive pathogenic potential highlight its role not only in human health but also in broader ecological contexts. The diverse host range signals the importance of monitoring this strain, particularly in clinical environments where it can contribute to significant morbidity and mortality. Understanding its traits and behavior is essential for developing strategies to mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT233

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT233
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT233 genome assembly,

Gene Summary

Adenine Count

1165995 bp

Thymine Count

1162787 bp

Guanine Count

1575302 bp

Cytosine Count

1549744 bp

Genome Length

5453828 bp

Protein-coding Genes

4893 genes

Non-Coding Genes

301 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
chaperone protein fimcSAMEA3538600_02794Not AvailablePositive2952604 - 295326624339.1
type 1 fimbriae anchoring protein fimdSAMEA3538600_02795Not AvailablePositive2953303 - 295585892593.5
fimbrial-like proteinSAMEA3538600_02796Not AvailablePositive2955866 - 295696037556.7
putative fimbrial adhesinSAMEA3538600_02797Not AvailableNegative2956973 - 295800136853.0
type 1 fimbriae anchoring protein fimdSAMEA3538600_02798Not AvailableNegative2958004 - 296054193255.5
pilin chaperoneSAMEA3538600_02799Not AvailableNegative2960571 - 296123924742.0
major type 1 subunit fimbrin (pilin)SAMEA3538600_02800Not AvailableNegative2961281 - 296182919143.6
putative transcriptional regulator of fimbrial expressionSAMEA3538600_02801Not AvailableNegative2961933 - 296263426779.0
putative abc-type amino acid transport/signal transduction systems periplasmic componentSAMEA3538600_02802Not AvailablePositive2962862 - 296375232211.7
putative transport proteinSAMEA3538600_02803Not AvailableNegative2963808 - 296442822942.6

Displaying genes 2971 – 2980 of 5194 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total