Klebsiella pneumoniae strain EuSCAPE_IT226

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT226 is a Gram-negative bacterium classified as a facultative anaerobe, capable of living in both aerobic and anaerobic environments. This strain exhibits a rod shape and can be found in various arrangements, including singles, pairs, and chains. It is motile due to the presence of flagella and thrives optimally at a temperature of 37°C, fitting into the mesophilic category. As a chemoheterotroph, K. pneumoniae utilizes organic compounds for energy, indicating its reliance on host-associated environments for sustenance. It is known to inhabit a wide range of hosts, including Homo sapiens, various animals such as Gallus gallus, Sus scrofa, and Danio rerio, among others. This broad host range suggests a versatile ecological niche, enabling the bacterium to adapt to different biological systems. K. pneumoniae strain EuSCAPE_IT226 is associated with numerous health complications, particularly in humans, where it can cause severe infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is nonsporulating, indicating it does not form spores, which may affect its survival strategies in adverse conditions. The presence of this strain in diverse hosts and its pathogenicity highlights its ecological adaptability and potential impact on public health. Understanding the traits and behaviors of K. pneumoniae can inform strategies to manage its infections and mitigate its spread in both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT226

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT226
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT226 genome assembly,

Gene Summary

Adenine Count

1228242 bp

Thymine Count

1222768 bp

Guanine Count

1634378 bp

Cytosine Count

1628938 bp

Genome Length

5714326 bp

Protein-coding Genes

5135 genes

Non-Coding Genes

409 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Terminase small subunitSAMEA3515254_00861Not AvailableNegative899330 - 89991422478.4
Hypothetical proteinSAMEA3515254_00862Not AvailableNegative899992 - 90024910011.8
Hypothetical proteinSAMEA3515254_00863Not AvailableNegative900324 - 90066212606.2
Hypothetical proteinSAMEA3515254_00864Not AvailableNegative900662 - 9009019069.38
Valyl-trna synthetaseSAMEA3515254_00865Not AvailableNegative900894 - 90156224681.9
Hypothetical proteinSAMEA3515254_00866Not AvailableNegative901559 - 9017717789.18
Hypothetical proteinSAMEA3515254_00867Not AvailableNegative901772 - 9019426375.24
Bcepny3gp60SAMEA3515254_00868Not AvailableNegative901942 - 90268528046.2
uncharacterised proteinSAMEA3515254_00869Not AvailableNegative902682 - 90310716786.9
Hypothetical proteinSAMEA3515254_00870Not AvailableNegative903104 - 9032957088.64

Displaying genes 31 – 40 of 5544 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total