Klebsiella pneumoniae strain EuSCAPE_IT221

Klebsiella pneumoniae strain EuSCAPE_IT221 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it adaptable to varying oxygen conditions. This strain is chemoheterotrophic, relying on organic compounds for energy. It typically forms chains, pairs, and singles, demonstrating a versatile cell arrangement. Mobility is facilitated by the presence of flagella, enhancing its ability to colonize different environments. EuSCAPE_IT221 is primarily associated with hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae. Its pathogenicity in humans is significant, as it is linked to a wide range of health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The optimal growth temperature for this mesophilic organism is 37°C, which aligns with the average human body temperature, facilitating its role as a human pathogen. With a single replicon and a double membrane structure, Klebsiella pneumoniae strain EuSCAPE_IT221 showcases typical characteristics of Enterobacteriaceae. Its nonsporulating nature suggests that it relies on other mechanisms for survival in adverse conditions. From an ecological perspective, the presence of this strain in various animal hosts indicates its adaptability and potential for zoonotic transmission, underscoring the importance of monitoring its prevalence in both human and animal populations to mitigate health risks associated with its pathogenicity.