Klebsiella pneumoniae strain EuSCAPE_IT103

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT103 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in varying oxygen conditions. It is classified as a chemoheterotroph, relying on organic compounds for energy. The bacterium typically organizes into chains, pairs, or exists as singles, and it possesses flagella, granting it mobility. This strain is predominantly found in association with hosts, including Homo sapiens and various animal species such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (domestic dogs), among others, indicating its versatility in infecting a wide range of organisms. Its optimal growth temperature is 37°C, placing it in the mesophilic range, which is conducive to its survival in warm-blooded hosts. Klebsiella pneumoniae strain EuSCAPE_IT103 is associated with numerous health complications, particularly in humans, where it can cause bacteremia, urinary tract infections, pneumonia, and a variety of other serious conditions such as sepsis and meningitis. The bacterium's pathogenicity is significant, highlighting its potential as a formidable opportunistic pathogen in various clinical settings. Understanding the ecological and biological interactions of Klebsiella pneumoniae strain EuSCAPE_IT103, particularly its free-living biotic relationship and ability to inhabit diverse hosts, underscores the importance of monitoring its prevalence and resistance patterns. This knowledge is crucial for developing effective strategies to combat infections caused by this strain, especially given its role in severe healthcare-associated infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT103

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT103
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT103 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4862 genes

Non-Coding Genes

260 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Cp4-57 prophageSAMEA3515132_01363Not AvailableNegative1411630 - 141282345034.6
Tmrna,resume;Not AvailableNot AvailablePositive1413006 - 1413368Not Available
Ssra-binding proteinSAMEA3515132_01365Not AvailableNegative1413513 - 141399518240.1
Type ii toxin-antitoxin system toxin rataSAMEA3515132_01366Not AvailablePositive1414145 - 141458216039.5
Rnfh family proteinSAMEA3515132_01367Not AvailablePositive1414572 - 141486210821.0
Outer membrane protein assembly factor bameSAMEA3515132_01368Not AvailableNegative1414929 - 141527012414.0
Dna repair protein recnSAMEA3515132_01369Not AvailableNegative1415418 - 141707961373.2
Dna repair protein recnSAMEA3515132_01370Not AvailableNegative1417166 - 141804432410.0
Heat shock proteinSAMEA3515132_01371Not AvailablePositive1418169 - 141875921751.9
Hlyc/corc family transporterSAMEA3515132_01372Not AvailableNegative1418879 - 142016548104.2

Displaying genes 61 – 70 of 5133 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total