Klebsiella pneumoniae strain EuSCAPE_IT214

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT214 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It is chemoheterotrophic, deriving its energy from organic compounds. This strain displays a characteristic cell arrangement in chains, pairs, or as singles, and it possesses flagella, enabling mobility. Optimal growth occurs at 37°C, within a mesophilic temperature range. This bacterium is primarily host-associated, with a diverse array of hosts, including Homo sapiens, Gallus gallus, various Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. Such a wide host range underscores its ecological versatility and potential for zoonotic transmission. Klebsiella pneumoniae strain EuSCAPE_IT214 is associated with a range of serious health effects, particularly in humans. Notable conditions linked to this strain include bacteremia, urinary tract infections, pneumonia, cystitis, intra-abdominal infections, and various forms of sepsis, among others. Its pathogenicity is significant in clinical settings, particularly in vulnerable populations such as neonates and individuals with compromised immune systems. Given its ability to thrive in diverse environments and its association with serious infections, Klebsiella pneumoniae strain EuSCAPE_IT214 exemplifies the complex interplay between human health and microbial ecology. The bacterium's presence in both human and animal hosts highlights the importance of monitoring and controlling its spread, especially in healthcare settings where it can lead to outbreaks of multidrug-resistant infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT214

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT214
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT214 genome assembly,

Gene Summary

Adenine Count

1241657 bp

Thymine Count

1247992 bp

Guanine Count

1656007 bp

Cytosine Count

1636361 bp

Genome Length

5782017 bp

Protein-coding Genes

5147 genes

Non-Coding Genes

406 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ligaseSAMEA3515242_01806Not AvailableNegative1869966 - 187076029165.5
lead, cadmium, zinc and mercury transporting atpaseSAMEA3515242_01807Not AvailableNegative1870892 - 187339387959.3
hth-type transcriptional regulator cuerSAMEA3515242_01808Not AvailablePositive1873500 - 187391015350.2
activity regulator of membrane protease ybbkSAMEA3515242_01809Not AvailableNegative1873907 - 187436516686.6
stomatin/prohibitin-family membrane protease subunit ybbkSAMEA3515242_01810Not AvailableNegative1874362 - 187527933562.8
ybbl abc transporter atp-binding proteinSAMEA3515242_01811Not AvailablePositive1875420 - 187609725230.1
ybbm seven transmembrane helix proteinSAMEA3515242_01812Not AvailablePositive1876084 - 187686628482.0
thioredoxin domain-containing protein ec-ybbnSAMEA3515242_01813Not AvailableNegative1876974 - 187782831775.8
short chain dehydrogenaseSAMEA3515242_01814Not AvailableNegative1877887 - 187865727861.9
multifunctional acyl-coa thioesterase i and protease i and lysophospholipase l1SAMEA3515242_01815Not AvailableNegative1878686 - 187986743974.4

Displaying genes 2051 – 2060 of 5553 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total