Klebsiella pneumoniae strain EuSCAPE_IT206

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT206 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its mobility, facilitated by the presence of flagella, and it typically forms chains, pairs, or singles. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This bacterium is primarily host-associated, with a wide variety of potential hosts, including Homo sapiens, Gallus gallus, and various other metazoans, indicating its ecological versatility. Klebsiella pneumoniae strain EuSCAPE_IT206 is involved in several significant health issues, including bacteremia, urinary tract infections, pneumonia, and meningitis, among others. The diverse range of infections it causes highlights its pathogenic potential in humans and animals alike. With a single replicon and a double membrane structure, Klebsiella pneumoniae demonstrates typical features of Gram-negative bacteria. Its nonsporulating nature and free-living biotic relationship further emphasize its adaptability in various environments. The strain’s capacity to cause severe infections, such as pyogenic liver abscesses and sepsis, underscores its importance in clinical microbiology and public health. Understanding the ecological role and pathogenicity of Klebsiella pneumoniae strain EuSCAPE_IT206 can provide insights into its transmission dynamics and the potential for outbreaks, particularly in healthcare settings where vulnerable populations may be at risk. Its presence in multiple hosts suggests a complex interplay between the bacterium and its environment, which warrants further investigation to mitigate its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT206

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT206
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT206 genome assembly,

Gene Summary

Adenine Count

1164285 bp

Thymine Count

1153682 bp

Guanine Count

1550800 bp

Cytosine Count

1565515 bp

Genome Length

5434282 bp

Protein-coding Genes

4975 genes

Non-Coding Genes

130 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dcrb proteinSAMEA3515234_03937Not AvailableNegative4223870 - 422442719526.3
preq0 transporterSAMEA3515234_03938Not AvailableNegative4224501 - 422516624984.9
trna 5-methylaminomethyl-2-thiouridine synthase tusaSAMEA3515234_03939Not AvailablePositive4225373 - 42256189260.33
lead, cadmium, zinc and mercury transporting atpaseSAMEA3515234_03940Not AvailableNegative4225722 - 422793277076.6
enzyme yhhnSAMEA3515234_03941Not AvailableNegative4228011 - 422863723639.8
putative receptorSAMEA3515234_03942Not AvailablePositive4228788 - 422913813071.8
membrane proteinSAMEA3515234_03943Not AvailableNegative4229152 - 422942710580.8
ribosomal rna small subunit methyltransferase dSAMEA3515234_03944Not AvailableNegative4229417 - 423001321952.2
signal recognition particle-docking protein ftsySAMEA3515234_03945Not AvailablePositive4230196 - 423171954958.9
cell division transporterSAMEA3515234_03946Not AvailablePositive4231722 - 423239024246.6

Displaying genes 3941 – 3950 of 5105 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total