Klebsiella pneumoniae strain EuSCAPE_IT017

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT017 is a gram-negative, facultative anaerobic bacterium with a rod shape, capable of mobility due to the presence of flagella. This strain is a chemoheterotroph that thrives at an optimal temperature of 37°C, fitting within the mesophilic temperature range. It is typically found in host-associated habitats and exhibits a variety of cell arrangements, including chains, pairs, and singles. This strain has significant implications for human health, being associated with a range of serious infections such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It can also cause life-threatening conditions, including sepsis and endophthalmitis, making it a notable pathogen in clinical settings. The strain has been documented to affect multiple hosts, including Homo sapiens (humans) and various animal species, indicating its adaptability and potential for cross-species transmission. Klebsiella pneumoniae EuSCAPE_IT017 is nonsporulating and possesses a single replicon and double membranes, characteristic of its classification within the Enterobacteriaceae family. The wide array of health effects associated with this bacterium underscores its role as a significant opportunistic pathogen. Understanding its ecology and pathogenicity is essential for developing effective treatment strategies and managing infections, particularly in vulnerable populations such as neonates and individuals with compromised immune systems. The ecological adaptability of Klebsiella pneumoniae underscores the importance of monitoring its prevalence in both human and veterinary contexts to mitigate its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT017

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT017
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT017 genome assembly,

Gene Summary

Adenine Count

1256091 bp

Thymine Count

1248589 bp

Guanine Count

1662025 bp

Cytosine Count

1650628 bp

Genome Length

5817333 bp

Protein-coding Genes

5161 genes

Non-Coding Genes

511 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative rz-like proteinSAMEA3538578_00884Not AvailableNegative941251 - 94173317816.9
EndolysinSAMEA3538578_00885Not AvailableNegative941730 - 94235923124.7
Putative holinSAMEA3538578_00886Not AvailableNegative942349 - 94265411320.0
Hypothetical proteinSAMEA3538578_00887Not AvailableNegative942641 - 94304514050.2
Putative bacterial proteinSAMEA3538578_00888Not AvailableNegative943169 - 9433215668.46
Tail spike proteinSAMEA3538578_00889Not AvailableNegative943330 - 94569985862.3
Hypothetical proteinSAMEA3538578_00890Not AvailablePositive945887 - 9461479908.88
Hypothetical proteinSAMEA3538578_00891Not AvailablePositive946238 - 9464959663.17
Putative anti-repressor proteinSAMEA3538578_00892Not AvailablePositive947317 - 94777217014.7
uncharacterised proteinSAMEA3538578_00893Not AvailablePositive947933 - 9481457925.74

Displaying genes 1 – 10 of 5672 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC6315841
Bloodstream infectionsCausesPMC6315841
Surgical site infectionsCausesPMC6315841

Displaying health effects 51 – 53 of 53 in total