Klebsiella pneumoniae strain EuSCAPE_IT013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IT013 is a Gram-negative, rod-shaped bacterium that exhibits a diverse host range, including Homo sapiens, various avian species, and several mammals such as Canis lupus familiaris and Sus scrofa. This strain is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, and it is identified as a chemoheterotroph, deriving energy from organic compounds. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. EuSCAPE_IT013 demonstrates mobility due to the presence of flagella and typically arranges itself in chains, pairs, or as single cells. With a single replicon and a dual-membrane structure, it is classified as free-living, which indicates its potential for environmental persistence and adaptability. This strain is notably pathogenic to humans, associated with a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to cause these infections underscores its significance in clinical microbiology, particularly in hospital settings where it can lead to severe complications such as septicemia and pulmonary infections. The ecological implications of Klebsiella pneumoniae strain EuSCAPE_IT013 extend beyond human health; its capability to inhabit various hosts suggests a complex interaction within different ecosystems. Understanding its pathogenicity and adaptability is crucial for developing effective infection control measures and therapeutic strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IT013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IT013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IT013 genome assembly,

Gene Summary

Adenine Count

1211747 bp

Thymine Count

1205248 bp

Guanine Count

1607587 bp

Cytosine Count

1605049 bp

Genome Length

5629631 bp

Protein-coding Genes

5065 genes

Non-Coding Genes

411 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane proteinSAMEA3538574_01025Not AvailablePositive1075294 - 107772988778.8
fimbrial subunitSAMEA3538574_01026Not AvailablePositive1077731 - 107875636157.8
putative gnat-family acetyltransferaseSAMEA3538574_01027Not AvailableNegative1078779 - 107964533705.1
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3538574_01028Not AvailablePositive1080156 - 108107635058.3
exported proteinSAMEA3538574_01029Not AvailablePositive1081177 - 10814499533.42
dna-binding transcriptional activator cadcSAMEA3538574_01030Not AvailablePositive1081742 - 108331057845.1
lysine/cadaverine antiporter membrane protein cadbSAMEA3538574_01031Not AvailablePositive1083676 - 108501046692.8
lysine decarboxylase 1SAMEA3538574_01032Not AvailablePositive1085093 - 108724081390.7
di/tripeptide permease yjdlSAMEA3538574_01033Not AvailablePositive1087300 - 108877552995.0
lysyl-trna synthetaseSAMEA3538574_01034Not AvailablePositive1089107 - 109062457654.8

Displaying genes 1341 – 1350 of 5476 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total