Klebsiella pneumoniae strain EuSCAPE_IL033

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IL033 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is classified as a chemoheterotroph and typically thrives at an optimal temperature of 37°C, fitting within the mesophilic temperature range. It exhibits a diverse cell arrangement, appearing in chains, pairs, and singles, and possesses a single replicon and two membranes. EuSCAPE_IL033 has significant implications for human health, being associated with a wide range of infections, including bacteremia, urinary tract infections, pneumonia, and sepsis. It is known to cause various other serious conditions such as meningitis, liver abscesses, and enteritis, highlighting its pathogenicity in humans. The strain can also affect a variety of hosts, including Homo sapiens, domestic animals like Gallus gallus (chickens), and other metazoans, indicating its adaptability to different biological environments. The ecological role of Klebsiella pneumoniae strain EuSCAPE_IL033 as a free-living organism suggests that it may contribute to microbial diversity in host-associated habitats. Its ability to thrive in diverse environments, paired with its pathogenic potential, underscores the importance of monitoring and understanding this strain in clinical and ecological contexts. This duality presents challenges for public health, as it can transition from a commensal to a pathogenic state, reflecting the complex interactions within host-associated microbiomes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IL033

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IL033
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IL033 genome assembly,

Gene Summary

Adenine Count

1210098 bp

Thymine Count

1212775 bp

Guanine Count

1625869 bp

Cytosine Count

1606562 bp

Genome Length

5655304 bp

Protein-coding Genes

5073 genes

Non-Coding Genes

401 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipopolysaccharide heptosyltransferase iiiSAMEA3538490_04497Not AvailableNegative4709550 - 471062640367.0
deacetylaseSAMEA3538490_04498Not AvailablePositive4710738 - 471170037518.4
heptosyl transferaseSAMEA3538490_04499Not AvailablePositive4711719 - 471279840840.7
polymeraseSAMEA3538490_04500Not AvailableNegative4712842 - 471401143477.5
lipopolysaccharide core biosynthesis protein rfazSAMEA3538490_04501Not AvailableNegative4713989 - 471489734468.7
lipopolysaccharide heptosyltransferase iSAMEA3538490_04502Not AvailableNegative4714897 - 471586835986.1
adp-heptose-lipooligosaccharide heptosyltransferase iiSAMEA3538490_04503Not AvailableNegative4715872 - 471689137859.8
adp-l-glycero-d-manno-heptose-6-epimeraseSAMEA3538490_04504Not AvailableNegative4716940 - 471787234941.0
2-amino-3-ketobutyrate coenzyme a ligaseSAMEA3538490_04505Not AvailablePositive4718086 - 471927943158.7
l-threonine 3-dehydrogenaseSAMEA3538490_04506Not AvailablePositive4719292 - 472031737229.1

Displaying genes 4661 – 4670 of 5474 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total