Klebsiella pneumoniae strain EuSCAPE_ME015

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ME015 is a pathogenic, Gram-negative bacterium primarily associated with humans (Homo sapiens) but also found in various other hosts, including birds (Gallus gallus), mammals (such as Canis lupus familiaris and Sus scrofa), and aquatic species (Danio rerio). This strain is a chemoheterotroph, utilizing organic compounds as its energy source, and it exhibits a mesophilic temperature range, with an optimal growth temperature of 37°C. The cellular arrangement of EuSCAPE_ME015 is characterized by chains, pairs, and singles, and it is rod-shaped with the presence of flagella, indicating motility. This bacterium is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. As a free-living organism, it can exist independently, although it poses significant health risks to its hosts, particularly humans. Klebsiella pneumoniae is known for causing a range of serious infections, including but not limited to bacteremia, urinary tract infections, pneumonia, and sepsis. It is associated with conditions such as intra-abdominal infections, liver abscesses, and neonatal sepsis, highlighting its pathogenic potential. The strain's ability to infect a broad range of hosts, coupled with its significant health impacts, emphasizes its ecological versatility and adaptability. This adaptability may contribute to its persistence in various environments and its capacity to cause infections across diverse species, underscoring the importance of monitoring and controlling its spread in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ME015

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ME015
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ME015 genome assembly,

Gene Summary

Adenine Count

1246400 bp

Thymine Count

1252136 bp

Guanine Count

1628581 bp

Cytosine Count

1639374 bp

Genome Length

5766491 bp

Protein-coding Genes

5191 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive3335958 - 3335979Not Available
Late control d family proteinSAMEA3538557_03091Not AvailableNegative3336370 - 333750941579.0
Tail sheath monomerSAMEA3538557_03092Not AvailablePositive3337664 - 333883642596.9
Major tail tube proteinSAMEA3538557_03093Not AvailablePositive3338836 - 333935118928.4
Tail proteinSAMEA3538557_03094Not AvailablePositive3339397 - 333971411303.7
Tail tape measure proteinSAMEA3538557_03095Not AvailablePositive3339859 - 3342834105324.0
Tail proteinSAMEA3538557_03096Not AvailablePositive3342850 - 334334118182.8
uncharacterised proteinSAMEA3538557_03097Not AvailablePositive3343586 - 334494452289.2
Tail fiber proteinSAMEA3538557_03098Not AvailableNegative3345098 - 334619538986.4
Hypothetical proteinSAMEA3538557_03099Not AvailableNegative3346195 - 33464078078.39

Displaying genes 1 – 10 of 5449 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
EpnCausesPMC7480896
Emphysematous pyelonephritisCausesPMC7480896
Pulmonary infectionCausesPMC8190614
Primary bacteremiaCausesPMC9427560
Urinary tract infectionsCausesPMC9427560
PneumoniaCausesPMC9427560
Intra-abdominal infectionsCausesPMC9427560
Wound infectionsCausesPMC9427560
PyonephrosisCausesPMC11729731
Psoas abscessCausesPMC11729731

Displaying health effects 31 – 40 of 53 in total