Klebsiella pneumoniae strain EuSCAPE_ME015

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ME015 is a pathogenic, Gram-negative bacterium primarily associated with humans (Homo sapiens) but also found in various other hosts, including birds (Gallus gallus), mammals (such as Canis lupus familiaris and Sus scrofa), and aquatic species (Danio rerio). This strain is a chemoheterotroph, utilizing organic compounds as its energy source, and it exhibits a mesophilic temperature range, with an optimal growth temperature of 37°C. The cellular arrangement of EuSCAPE_ME015 is characterized by chains, pairs, and singles, and it is rod-shaped with the presence of flagella, indicating motility. This bacterium is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. As a free-living organism, it can exist independently, although it poses significant health risks to its hosts, particularly humans. Klebsiella pneumoniae is known for causing a range of serious infections, including but not limited to bacteremia, urinary tract infections, pneumonia, and sepsis. It is associated with conditions such as intra-abdominal infections, liver abscesses, and neonatal sepsis, highlighting its pathogenic potential. The strain's ability to infect a broad range of hosts, coupled with its significant health impacts, emphasizes its ecological versatility and adaptability. This adaptability may contribute to its persistence in various environments and its capacity to cause infections across diverse species, underscoring the importance of monitoring and controlling its spread in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ME015

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ME015
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ME015 genome assembly,

Gene Summary

Adenine Count

1246400 bp

Thymine Count

1252136 bp

Guanine Count

1628581 bp

Cytosine Count

1639374 bp

Genome Length

5766491 bp

Protein-coding Genes

5191 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein yraqSAMEA3538557_02363Not AvailablePositive2577012 - 257805237011.5
hemolysinSAMEA3538557_02364Not AvailableNegative2578174 - 257874920067.1
dnaa initiator-associating protein diaaSAMEA3538557_02365Not AvailableNegative2578759 - 257934921093.3
endonucleaseSAMEA3538557_02366Not AvailableNegative2579375 - 257976114465.1
lppc putative lipoproteinSAMEA3538557_02367Not AvailableNegative2579719 - 258182775027.7
rrna small subunit methyltransferase iSAMEA3538557_02368Not AvailablePositive2581891 - 258275431536.9
d-galactarate dehydrataseSAMEA3538557_02369Not AvailableNegative2582955 - 258452656128.5
uncharacterised proteinSAMEA3538557_02370Not AvailablePositive2584709 - 25848585477.89
galactonate transporterSAMEA3538557_02371Not AvailablePositive2584919 - 258625048607.5
2-dehydro-3-deoxyglucarate aldolaseSAMEA3538557_02372Not AvailablePositive2586277 - 258704727232.6

Displaying genes 2561 – 2570 of 5449 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total